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Table 4 Odds of use of Antipsychotics or Antidepressants at one time point given use of Antipsychotics or Antidepressants at the previous time point, covariates measured at the “previous” time point, N = 1406 observations

From: Persistent use of psychotropic drugs in nursing home residents in Norway

Variables

Antipsychotics

Antidepressants

Unadjusted

Adjusted

Unadjusted

Adjusted

OR (95% CI)

P-value

OR (95% CI)

P-value

OR (95% CI)

P-value

OR (95% CI)

P-value

Assessed at previous time point

 CDR sum of boxes

1.04 (1.002; 1.07)

0.036

  

0.97 (0.95; 0.995)

0.020

  

 GMHR

        

  Good

1.25 (0.66; 2.37)

0.498

  

0.98 (0.59; 1.63)

0.934

0.63 (0.35; 1.12)3

0.111

  Fairly good

1.11 (0.63; 1.98)

0.715

  

1.29 (0.82; 2.02)

0.273

0.92 (0.56; 1.51)8

0.745

  Poor

1.53 (0.86; 2.72)

0.151

  

1.62 (1.03; 2.56)

0.038

1.34 (0.83; 2.16)5

0.229

  Very Poor

1

-

  

1

-

1

-

 PSMS score

1.03 (0.997; 1.06)

0.073

  

0.96 (0.94; 0.98)

0.001

0.94 (0.91; 0.97)2

<0.001

 NPI Agitation sub-syndrome

1.05 (1.03; 1.07)

<0.001

1.02 (0.997; 1.04)6

0.093

0.997 (0.98; 1.01)

0.714

  

 NPI Psychosis sub-syndrome

1.09 (1.06; 1.12)

<0.001

1.06 (1.03; 1.10)2

0.001

1.00 (0.98; 1.03)

0.915

0.97 (0.95; 1.00)4

0.060

 NPI Affective sub-syndrome

1.06 (1.03; 1.09)

<0.001

1.03 (0.999; 1.07)5

0.060

1.08 (1.05; 1.10)

<0.001

1.08 (1.05; 1.11)1

<0.001

 NPI Apathy

1.07 (1.03; 1.12)

<0.001

  

0.99 (0.96; 1.03)

0.732

  

Assessed at baseline

 Age

0.95 (0.93; 0.97)

<0.001

0.95 (0.93; 0.97)1

<0.001

0.99 (0.98; 1.01)

0.317

0.98 (0.97; 1.00)6

0.056

 Females

0.56 (0.40; 0.80)

0.001

0.64 (0.44; 0.93)4

0.019

1.38 (1.02; 1.87)

0.035

1.33 (0.97; 1.82)7

0.078

 Education (<=10 years)

0.97 (0.68; 1.39)

0.865

  

0.88 (0.66; 1.17)

0.385

  

 Duration in NH (LN)

1.21 (1.06; 1.40)

0.007

1.21 (1.05; 1.40)3

0.011

0.98 (0.88; 1.09)

0.654

  

 Nursing home size

0.998 (0.993; 1.003)

0.382

  

1.00 (0.998; 1.01)

0.347

  

 Type of nursing home unit

        

  RU

1

-

  

1

-

  

  REU

0.57 (0.10; 3.41)

0.539

  

1.03 (0.30; 3.51)

0.959

  

  SCU

1.24 (0.78; 1.97)

0.367

  

0.80 (0.55; 1.17)

0.248

  

  OU

3.25 (0.63; 16.81)

0.160

  

1.13 (0.28; 4.61)1

0.865

  
  1. RU Regular units
  2. REU rehabilitation unit
  3. SCU special care unit for people with dementia
  4. OU other units
  5. The relative importance of each covariate in the adjusted models is included with a number after the 95% CI; lowest number has highest importance