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Table 4 Odds of use of Antipsychotics or Antidepressants at one time point given use of Antipsychotics or Antidepressants at the previous time point, covariates measured at the “previous” time point, N = 1406 observations

From: Persistent use of psychotropic drugs in nursing home residents in Norway

Variables Antipsychotics Antidepressants
Unadjusted Adjusted Unadjusted Adjusted
OR (95% CI) P-value OR (95% CI) P-value OR (95% CI) P-value OR (95% CI) P-value
Assessed at previous time point
 CDR sum of boxes 1.04 (1.002; 1.07) 0.036    0.97 (0.95; 0.995) 0.020   
 GMHR         
  Good 1.25 (0.66; 2.37) 0.498    0.98 (0.59; 1.63) 0.934 0.63 (0.35; 1.12)3 0.111
  Fairly good 1.11 (0.63; 1.98) 0.715    1.29 (0.82; 2.02) 0.273 0.92 (0.56; 1.51)8 0.745
  Poor 1.53 (0.86; 2.72) 0.151    1.62 (1.03; 2.56) 0.038 1.34 (0.83; 2.16)5 0.229
  Very Poor 1 -    1 - 1 -
 PSMS score 1.03 (0.997; 1.06) 0.073    0.96 (0.94; 0.98) 0.001 0.94 (0.91; 0.97)2 <0.001
 NPI Agitation sub-syndrome 1.05 (1.03; 1.07) <0.001 1.02 (0.997; 1.04)6 0.093 0.997 (0.98; 1.01) 0.714   
 NPI Psychosis sub-syndrome 1.09 (1.06; 1.12) <0.001 1.06 (1.03; 1.10)2 0.001 1.00 (0.98; 1.03) 0.915 0.97 (0.95; 1.00)4 0.060
 NPI Affective sub-syndrome 1.06 (1.03; 1.09) <0.001 1.03 (0.999; 1.07)5 0.060 1.08 (1.05; 1.10) <0.001 1.08 (1.05; 1.11)1 <0.001
 NPI Apathy 1.07 (1.03; 1.12) <0.001    0.99 (0.96; 1.03) 0.732   
Assessed at baseline
 Age 0.95 (0.93; 0.97) <0.001 0.95 (0.93; 0.97)1 <0.001 0.99 (0.98; 1.01) 0.317 0.98 (0.97; 1.00)6 0.056
 Females 0.56 (0.40; 0.80) 0.001 0.64 (0.44; 0.93)4 0.019 1.38 (1.02; 1.87) 0.035 1.33 (0.97; 1.82)7 0.078
 Education (<=10 years) 0.97 (0.68; 1.39) 0.865    0.88 (0.66; 1.17) 0.385   
 Duration in NH (LN) 1.21 (1.06; 1.40) 0.007 1.21 (1.05; 1.40)3 0.011 0.98 (0.88; 1.09) 0.654   
 Nursing home size 0.998 (0.993; 1.003) 0.382    1.00 (0.998; 1.01) 0.347   
 Type of nursing home unit         
  RU 1 -    1 -   
  REU 0.57 (0.10; 3.41) 0.539    1.03 (0.30; 3.51) 0.959   
  SCU 1.24 (0.78; 1.97) 0.367    0.80 (0.55; 1.17) 0.248   
  OU 3.25 (0.63; 16.81) 0.160    1.13 (0.28; 4.61)1 0.865   
  1. RU Regular units
  2. REU rehabilitation unit
  3. SCU special care unit for people with dementia
  4. OU other units
  5. The relative importance of each covariate in the adjusted models is included with a number after the 95% CI; lowest number has highest importance