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Table 3 Odds ratios for use of each category of psychotropic drugs at one time point given use of the same category of the psychotropic drug at an earlier time point (the distance between time points is called lag), unadjusted and adjusted analyses where relevant covariates adjusted for were measured at the same earlier time

From: Persistent use of psychotropic drugs in nursing home residents in Norway

Variables Unadjusted Adjusted
OR (95% CI) P-value OR (95% CI) P-value
Lag 1, N = 1406 observations
 Antipsychoticsa 30.7 (21.8; 43.1) <0.001 28.8 (20.31; 40.8) <0.001
 Antidepressantsb 32.6 (23.8; 44.8) <0.001 34.1 (24.6; 47.4) <0.001
 Anxiolyticsc 33.1 (23.7; 46.2) <0.001 32.2 (23.1; 45.0) <0.001
 Sedativesd 22.6 (15.6; 30.8) <0.001 23.1 (16.8; 31.7) <0.001
Lag 2, N = 654 observations
 Antipsychoticse 13.3 (8.3; 21.4) <0.001 13.5 (8.1; 22.3) <0.001
 Antidepressantsf 15.5 (9.9; 24.2) <0.001 16.0 (10.2; 25.3) <0.001
 Anxiolyticsg 21.4 (12.8; 35.7) <0.001 23.4 (13.9; 39.6) <0.001
 Sedativesh 9.3 (5.9; 14.4) <0.001 9.4 (5.9; 14.8) <0.001
Lag 3, N = 288 observations
 Antipsychoticsi 16.5 (7.5; 36.3) <0.001 17.9 (7.5; 42.4) <0.001
 Antidepressantsj 10.0 (4.9; 20.4) <0.001 12.6 (5.8; 27.2) <0.001
 Anxiolyticsk 14.4 (6.5; 32.1) <0.001 14.3 (7.0; 29.2) <0.001
 Sedativesl 7.0 (3.6; 13.9) <0.001 6.4 (3.2; 12.6) <0.001
  1. Lag 1: two consecutive assessment time points
  2. Lag 2: one time point between selected time points
  3. Lag 3: two time points between selected time points
  4. aAdjusted for: PSMS score, NPI Agitation sub-syndrome, NPI Psychosis sub-syndrome, NPI Affective sub-syndrome, NH size age and duration in NH
  5. bAdjusted for: PSMS score, NPI- Affective sub-syndrome, NPI Apathy and duration in NH
  6. cAdjusted for CDR sum of boxes, NPI- Affective sub-syndrome and level of education
  7. dAdjusted for PSMS score, NPI Apathy and duration in NH
  8. eAdjusted for PSMS score, NPI Psychosis sub-syndrome, NPI Apathy, Type of nursing home and age
  9. fAdjusted for: CDR sum of boxes, PSMS score and NPI- Affective sub-syndrome
  10. gAdjusted for CDR sum of boxes, PSMS score and level of education
  11. hAdjusted for CDR sum of boxes, PSMS and age
  12. iAdjusted for PSMS score and age
  13. jAdjusted for: CDR sum of boxes, NPI- Affective sub-syndrome and NPI Apathy
  14. kAdjusted for NPI Agitation sub-syndrome, NPI Psychosis sub-syndrome, NPI Affective sub-syndrome, NPI Apathy, level of education and Type of nursing home unit
  15. lAdjusted for CDR sum of boxes, NPI Psychosis sub-syndrome and Nursing home size