Variables
|
Unadjusted
|
Adjusted
|
---|
OR (95% CI)
|
P-value
|
OR (95% CI)
|
P-value
|
---|
Lag 1, N = 1406 observations
|
Antipsychoticsa
|
30.7 (21.8; 43.1)
|
<0.001
|
28.8 (20.31; 40.8)
|
<0.001
|
Antidepressantsb
|
32.6 (23.8; 44.8)
|
<0.001
|
34.1 (24.6; 47.4)
|
<0.001
|
Anxiolyticsc
|
33.1 (23.7; 46.2)
|
<0.001
|
32.2 (23.1; 45.0)
|
<0.001
|
Sedativesd
|
22.6 (15.6; 30.8)
|
<0.001
|
23.1 (16.8; 31.7)
|
<0.001
|
Lag 2, N = 654 observations
|
Antipsychoticse
|
13.3 (8.3; 21.4)
|
<0.001
|
13.5 (8.1; 22.3)
|
<0.001
|
Antidepressantsf
|
15.5 (9.9; 24.2)
|
<0.001
|
16.0 (10.2; 25.3)
|
<0.001
|
Anxiolyticsg
|
21.4 (12.8; 35.7)
|
<0.001
|
23.4 (13.9; 39.6)
|
<0.001
|
Sedativesh
|
9.3 (5.9; 14.4)
|
<0.001
|
9.4 (5.9; 14.8)
|
<0.001
|
Lag 3, N = 288 observations
|
Antipsychoticsi
|
16.5 (7.5; 36.3)
|
<0.001
|
17.9 (7.5; 42.4)
|
<0.001
|
Antidepressantsj
|
10.0 (4.9; 20.4)
|
<0.001
|
12.6 (5.8; 27.2)
|
<0.001
|
Anxiolyticsk
|
14.4 (6.5; 32.1)
|
<0.001
|
14.3 (7.0; 29.2)
|
<0.001
|
Sedativesl
|
7.0 (3.6; 13.9)
|
<0.001
|
6.4 (3.2; 12.6)
|
<0.001
|
- Lag 1: two consecutive assessment time points
- Lag 2: one time point between selected time points
- Lag 3: two time points between selected time points
-
aAdjusted for: PSMS score, NPI Agitation sub-syndrome, NPI Psychosis sub-syndrome, NPI Affective sub-syndrome, NH size age and duration in NH
-
bAdjusted for: PSMS score, NPI- Affective sub-syndrome, NPI Apathy and duration in NH
-
cAdjusted for CDR sum of boxes, NPI- Affective sub-syndrome and level of education
-
dAdjusted for PSMS score, NPI Apathy and duration in NH
-
eAdjusted for PSMS score, NPI Psychosis sub-syndrome, NPI Apathy, Type of nursing home and age
-
fAdjusted for: CDR sum of boxes, PSMS score and NPI- Affective sub-syndrome
-
gAdjusted for CDR sum of boxes, PSMS score and level of education
-
hAdjusted for CDR sum of boxes, PSMS and age
-
iAdjusted for PSMS score and age
-
jAdjusted for: CDR sum of boxes, NPI- Affective sub-syndrome and NPI Apathy
-
kAdjusted for NPI Agitation sub-syndrome, NPI Psychosis sub-syndrome, NPI Affective sub-syndrome, NPI Apathy, level of education and Type of nursing home unit
-
lAdjusted for CDR sum of boxes, NPI Psychosis sub-syndrome and Nursing home size