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Table 2 Prevalence and persistence of PTD use according to the presence of dementia at each assessment (%)

From: Persistent use of psychotropic drugs in nursing home residents in Norway

 

Prevalence in percentages

A1

A2

A3

A4

A5

All

(n = 1163)

D/nD

(n = 932/227)

All

(n = 789)

D/nD

(n = 628/159)

All

(n = 395)

D/nD

(n = 300/94)

All (n = 209)

D/nD

(n = 160/48)

All (n = 98)

D/nD

(n = 75/22)

Antipsychotics (AP)

24.1

26.0/15.9***

25.2

26.4/20.8

20.5

22.0/16.0

20.6

22.5/14.6

20.4

20.0/22.7

 Trad. AP

11.3

11.5/11.0

12.2

11.6/14.5

9.4

9.0/10.6

8.6

9.4/6.3

12.2

12.0/13.6

 Atypical AP

13.2

14.9/5.7***

13.8

15.6/6.9***

11.9

13.7/6.4**

12.6

13.1/8.3

8.2

8.0/9.1

Antidepressants

38.3

39.1/34.8

37.3

37.9/34.0

36.7

35.3/40.4

35.4

33.1/41.7

32.7

29.3/40.9

Anxiolytics

24.2

23.8/26.4

24.2

22.9/29.6*

25.1

21.3/37.2***

28.7

26.9/35.4

22.4

21.3/27.3

Sedatives

29.0

26.4/39.6***

26.6

23.4/38.4***

24.1

21.0/33.0*

23.9

19.4/37.5**

23.5

20.0/31.8

Antidementia drug

11.3

13.5/2.2***

9.8

11.8/1.9***

5.3

6.3/2.1*

2.9

3.1/2.1

0

0/0

Any PTD

72.9

74.5/66.5*

71.4

71.5/70.4

70.4

67.7/78.7*

69.4

66.9/77.1

63.3

57.3/81.8**

 

Persistence at two consecutive time points in percentages

 

A1–A2

A2–A3

A3–A4

A4–A5

  

All

D/nD

All

D/nD

All

D/nD

All

D/nD

Antipsychotics (AP)

  

76.7

75.2/88.9*

64.9

67.6/55.0

69.6

67.5/83.3

70.0

68.8/75.0

 Trad. AP

  

73.6

70.8/84.2

61.4

63.3/57.1

73.7

73.3/75.0

80.0

75.0/100

 Atypical AP

  

74.5

74.7/80.0

61.5

63.0/50.0

62.1

59.3/100***

60.0

62.5/50.0

Antidepressants

  

80.4

79.8/82.8

76.5

73.1/87.9*

72.2

66.1/89.5**

75.7

76.9/70.0

Anxiolytics

  

76.9

73.6/89.5**

69.2

62.7/84.4**

86.8

82.1/100**

66.7

66.7/66.7

Sedatives

  

70.9

65.8/82.8**

64.8

69.1/55.6

69.6

64.9/77.8

68.0

58.8/85.7

Antidementia drug

  

66.0

65.3/100***

38.1

36.6/100***

27.3

27.3/0

0

0/0

Any PTD

  

89.8

88.7/94.3*

85.3

82.4/94.2**

89.3

86.6/97.3**

78.4

75.5/85.0

  1. A1–A5: Assessment 1–5
  2. D Dementia CDR ≥ 1; nD No dementia CDR < 1
  3. CDR ratings were missing for 4 people at A1, 2 people at A2 and 2 people at A3
  4. CDR Clinical Dementia Rating scale
  5. Trad Conventional
  6. PTD Psychotropic drugs
  7. *p < 0.05, **p ≤ 0.01; ***p ≤ 0.001 (Z-test for proportions used)