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Table 2 Study characteristics

From: Variation in use of antipsychotic medications in nursing homes in the United States: A systematic review

Author

Study Title

Journal

Study Design

Total Pt. #

Total NH #

Sample Rep.

Bonner AF, Field TS, Lemay CA, et al., 2015

Rationales that providers and family members cited for the use of antipsychotic medications in nursing home residents with dementia

Journal of the American Geriatrics Society

Qualitative, descriptive

204

26

5 CMS regions:

(III, IV, VIII, IX)

Bowblis JR, Crystal S, Intrator O, et al., 2012

Response to regulatory stringency: the case of antipsychotic medication use in nursing homes

Health Economics

Retrospective cohort

NA

14,743

48 states

Briesacher BA, Limcangco MR, Simoni-Wastila L, et al., 2005

The quality of antipsychotic drug prescribing in nursing homes

Archives of Internal Medicine

Retrospective cohort

1,096

NA

national

Briesacher BA, Tjia J, Field T, et al., 2013

Antipsychotic use among nursing home residents

JAMA

Retrospective cohort

1,402,039 & 561,681*

5,038

48 states

Castle NG, Hanlon JT, Handler SM, 2009

Results of a longitudinal analysis of national data to examine relationships between organizational and market characteristics and changes in antipsychotic prescribing in US nursing homes from 1996 through 2006

American Journal of Geriatric Pharmacotherapy

Retrospective cohort

NA

15,155 & 17,213**

national

Chen Y, Briesacher BA, Field TS, et al., 2010

Unexplained variation across US nursing homes in antipsychotic prescribing rates

Archives of Internal Medicine

Retrospective cross sectional

16,586

1,257

national

Hughes CM, Lapane KL, Mor V, 2000

Influence of facility characteristics on use of antipsychotic medications in nursing homes

Medical Care

Cross sectional

NA

14,631

national

Huybrechts KF, Rothman KJ, Brookhart MA, et al., 2012

Variation in antipsychotic treatment choice across US nursing homes

Journal of Clinical Psychopharmacology

Retrospective cohort

65,618

5,751

45 states

Kamble P, Chen H, Sherer J, Aparasu RR, 2008

Antipsychotic drug use among elderly nursing home residents in the United States

American Journal of Geriatric Pharmacotherapy

Cross sectional

11,227

1,174

national

Kamble P, Chen H, Sherer J, Aparasu R, 2009

Use of antipsychotics among elderly nursing home residents with dementia in the US: an analysis of National Survey Data

Drugs & Aging

Cross sectional

6,103

1,174

national

Kamble P, Sherer J, Chen H, Aparasu R, 2010

Off-label use of second-generation antipsychotic agents among elderly nursing home resident.

Psychiatric Services

Retrospective cross sectional

2,605

1,174

national

Konetzka RT, Brauner DJ, Shega J, et al., 2014

The effects of public reporting on physical restraints and antipsychotic use in nursing home residents with severe cognitive impairment

Journal of the American Geriatrics Society

Retrospective cohort

809, 645

4,258

6 states:

CA,FL,

IL,NY,

OH,TX

Lester P, Kohen I, Stefanacci RG, Feuerman M, 2011

Antipsychotic drug use since the FDA black box warning: survey of nursing home policies

Journal of the American Medical Directors Association

Cross sectional (survey)

NA

250

national

Lucas JA, Chakravarty S, Bowblis JR, et al., 2014

Antipsychotic medication use in nursing homes: a proposed measure of quality

International Journal of Geriatric Psychiatry

Cross sectional

155,095

NA

7 states: CA, FL, GA, IL, NJ, OH, TX

Miller SC, Papandonatos G, Fennell M, Mor V, 2006

Facility and county effects on racial differences in nursing home quality indicators

Social Science & Medicine

Cross sectional

63,932

408

NY

Pimentel CB, Donovan JL, Field TS, et al., 2015

Use of atypical antipsychotics in nursing homes and pharmaceutical marketing

Journal of the American Geriatrics Society

Nested mixed-methods, cross-sectional study of NHs in a cluster randomized trial

93

41

CT

Stevenson DG, Decker SL, Dwyer LL, et al., 2010

Antipsychotic and benzodiazepine use among nursing home residents: findings from the 2004 National Nursing Home Survey

American Journal of Geriatric Psychiatry

Cross Sectional

12,090

1,174

national

Svarstad BL, Mount JK, Bigelow W, 2001

Variations in the treatment culture of nursing homes and responses to regulations to reduce drug use

Psychiatric Services

Longitudinal cohort

1,181

16

WI

Tjia J, Field T, Lemay C, et al., 2014

Antipsychotic use in nursing homes varies by psychiatric consultant

Medical Care

Nested cross sectional study of NHs in a cluster randomized trial

NA

60

national

  1. NA not available, NH nursing home, Pt patient
  2. Sample Rep.: sample represented in study
  3. *overall sample and subset observed continuously for at least 90 days
  4. **sample in 1996 and sample in 2006