Potential unfavorable impacts of BDNF Val66Met polymorphisms on metabolic risks in average population in a longevous area

Table 1 Population characteristic and metabolic parameters of participants

Parameter	LG (n = 487)	OG (n = 593)	CG (n = 582)	F(χ ² )	P
Age (years)	93.28 ± 2.87*^▲	58.35 ± 9.06	58.18 ± 9.77	3239.680	0.000
Male/Female	200/287	333/260	328/254	31.813	0.000
WC (cm)	76.23 ± 9.14	75.08 ± 9.27	75.53 ± 9.41	0.340	0.712
BMI (kg/m²)	20.21 ± 3.63	21.68 ± 3.00	21.69 ± 3.24	0.022	0.978
FPG (mmol/L)	4.65 ± 1.18^▲	4.97 ± 1.80*	4.73 ± 1.52	8.070	0.000
SBP (mm Hg)	165.83 ± 26.15	137.81 ± 22.96	136.02 ± 23.56	0.618	0.539
DBP (mm Hg)	89.21 ± 13.17*^▲	85.15 ± 11.22	84.68 ± 11.31	4.020	0.018
PP (mm Hg)	76.61 ± 23.74	52.66 ± 19.81	51.34 ± 18.40	2.484	0.084
TC (mmol/L)	5.09 ± 1.00*	5.31 ± 1.13*	4.88 ± 1.00	28.690	0.000
TG (mmol/L)	0.97(0.45)	1.00(0.89)	0.95(0.66)	2.150	0.117
HDL-C (mmol/L)	1.61 ± 0.53	1.71 ± 0.57*	1.62 ± 0.50	3.353	0.035
LDL-C (mmol/L)	2.99 ± 0.87*	2.99 ± 1.04*	2.61 ± 0.92	27.325	0.000

Abbreviations: LG long-lived group, OG offspring group, CG control group, WC waist circumference, BMI body mass index, FPG fasting plasma glucose, SBP systolic blood pressure, DBP diastolic blood pressure, PP pulse pressure, TC total cholesterol, TG triglyceride (presented as median and interquartile range), HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol
^▲ vs OG, P <0.05; *vs CG, P <0.05

ISSN: 1471-2318