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Table 5 Association of pro-inflammatory burden scores with prevalent peripheral arterial disease

From: Prevalent peripheral arterial disease and inflammatory burden

Model Pro-inflammatory burden score
Odds Ratio (95% Confidence Interval)a
1 2 ≥3 P for trend
Crude model 1.57 (0.71, 3.45) 0.96 (0.33, 2.78) 3.92 (1.96, 7.85) 0.002
Age-adjusted model 1.62 (0.73, 3.59) 0.85 (0.29, 2.48) 3.11 (1.52, 6.35) 0.025
Conditions-adjusted modelb 1.79 (0.79, 4.06) 1.01 (0.34, 2.98) 3.65 (1.75, 7.63) 0.008
Medications-adjusted modelc 2.13 (0.90, 5.06) 1.30 (0.42, 3.98) 4.29 (1.93, 9.54) 0.004
Multivariate-adjusted modeld 2.40 (0.95, 6.07) 1.27 (0.39, 4.15) 3.59 (1.48, 8.71) 0.031
Multivariate-adjusted model + smoking status 2.25 (0.87, 5.78) 1.15 (0.35, 3.79) 2.88 (1.17, 7.13) 0.097
Multivariate-adjusted model + smoking pack-years 2.42 (0.93, 6.27) 1.28 (0.38, 4.25) 3.29 (1.33, 8.15) 0.052
Multivariate-adjusted model + CVD risk factorse 2.87 (1.06, 7.79) 1.31 (0.37, 4.67) 4.88 (1.86, 12.79) 0.013
  1. aReference group = pro-inflammatory burden score of zero
  2. bConditions-adjusted model was adjusted for MI, hypertension, CHF, COPD, diabetes status
  3. cMedications-adjusted model was adjusted for NSAID, Aspirin, cox-II inhibitor, ACE inhibitors, loop diuretics, antidepressants
  4. dMultivariate-adjusted models were adjusted for age, MI, hypertension, CHF, COPD, diabetes status, NSAID, Aspirin, cox-II inhibitor, ACE inhibitors, loop diuretics, antidepressants, self-rated health status, BMI, PASE score, walking speed
  5. eCVD risk factors included systolic blood pressure, fasting blood glucose, total cholesterol and HDL
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