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Table 5 Association of pro-inflammatory burden scores with prevalent peripheral arterial disease

From: Prevalent peripheral arterial disease and inflammatory burden

Model

Pro-inflammatory burden score

Odds Ratio (95% Confidence Interval)a

1

2

≥3

P for trend

Crude model

1.57 (0.71, 3.45)

0.96 (0.33, 2.78)

3.92 (1.96, 7.85)

0.002

Age-adjusted model

1.62 (0.73, 3.59)

0.85 (0.29, 2.48)

3.11 (1.52, 6.35)

0.025

Conditions-adjusted modelb

1.79 (0.79, 4.06)

1.01 (0.34, 2.98)

3.65 (1.75, 7.63)

0.008

Medications-adjusted modelc

2.13 (0.90, 5.06)

1.30 (0.42, 3.98)

4.29 (1.93, 9.54)

0.004

Multivariate-adjusted modeld

2.40 (0.95, 6.07)

1.27 (0.39, 4.15)

3.59 (1.48, 8.71)

0.031

Multivariate-adjusted model + smoking status

2.25 (0.87, 5.78)

1.15 (0.35, 3.79)

2.88 (1.17, 7.13)

0.097

Multivariate-adjusted model + smoking pack-years

2.42 (0.93, 6.27)

1.28 (0.38, 4.25)

3.29 (1.33, 8.15)

0.052

Multivariate-adjusted model + CVD risk factorse

2.87 (1.06, 7.79)

1.31 (0.37, 4.67)

4.88 (1.86, 12.79)

0.013

  1. aReference group = pro-inflammatory burden score of zero
  2. bConditions-adjusted model was adjusted for MI, hypertension, CHF, COPD, diabetes status
  3. cMedications-adjusted model was adjusted for NSAID, Aspirin, cox-II inhibitor, ACE inhibitors, loop diuretics, antidepressants
  4. dMultivariate-adjusted models were adjusted for age, MI, hypertension, CHF, COPD, diabetes status, NSAID, Aspirin, cox-II inhibitor, ACE inhibitors, loop diuretics, antidepressants, self-rated health status, BMI, PASE score, walking speed
  5. eCVD risk factors included systolic blood pressure, fasting blood glucose, total cholesterol and HDL