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Table 1 Characteristics of AD and non-AD cohorts

From: Comparison of predictors of hip fracture and mortality after hip fracture in community-dwellers with and without Alzheimer’s disease – exposure-matched cohort study

Characteristic AD cohort N = 67,072 Non-AD cohort N = 67,072 P
Age at baseline, mean (95% CI) 79.9 (79.8–79.9) 79.9 (79.8–79.9) matched
Age at first fracture during the follow-up 84.1 (83.9–84.3) 86.3 (86.1–86.5) <0.001
Sex    
 Men 43158 (64.3) 43158 (64.3) matched
 Women 23914 (35.7) 23914 (35.7)  
Highest occupational social class before follow-up   
 Managerial/professional 14072 (21.0) 14454 (21.5) <0.001
 Office worker 5608 (8.4) 5629 (8.4)  
 Farming/forestry 12735 (19.0) 13160 (19.6)  
 Sales/industry/cleaning 28669 (42.7) 26180 (39.0)  
 Unknown 5470 (8.2) 5186 (7.7)  
 Did not respond 518 (0.8) 2463 (3.7)  
Hip replacement 2219 (3.3) 1001 (1.5) <0.001
Knee replacement 105 (0.2) 67 (0.1) 0.004
Cardiovascular disease 34046 (50.8) 32841 (49.0) <0.001
Stroke 6356 (9.5) 5232 (7.8) <0.001
Diabetes 8969 (13.4) 7527 (11.2) <0.001
Asthma/COPD 5846 (8.7) 6011 (9.0) 0.11
Cancer treatment 792 (1.2) 855 (1.3) 0.12
Any mental or behavioural disorder 15365 (22.9) 5917 (8.8) <0.001
Any CVD medication 57603 (85.9) 54704 (81.6) <0.001
Drugs for obstructive airway diseases 15895 (23.7) 15991 (23.8) 0.54
Hormone therapy use 4429 (6.6) 4213 (6.3) 0.16
Bisphosphonates 8932 (13.3) 7460 (11.1) <0.001
Proton pump inhibitors 22281 (33.2) 21760 (32.4) 0.002
Anti-Parkinson drugs 2349 (3.5) 1959 (2.9) <0.001
Antiepileptics drugs 6729 (10.0) 5697 (8.5) <0.001
Antipsychotics 11127 (16.6) 5364 (8.0) <0.001
Antidepressants 23044 (34.4) 13821 (20.6) <0.001
Benzodiazepines and related drugs 29368 (43.8) 25915 (38.6) <0.001
Opioids 28907 (43.1) 25742 (38.4) <0.001
  1. Data are given as n (%) unless otherwise indicated
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