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Table 1 Characteristics of AD and non-AD cohorts

From: Comparison of predictors of hip fracture and mortality after hip fracture in community-dwellers with and without Alzheimer’s disease – exposure-matched cohort study

Characteristic

AD cohort N = 67,072

Non-AD cohort N = 67,072

P

Age at baseline, mean (95% CI)

79.9 (79.8–79.9)

79.9 (79.8–79.9)

matched

Age at first fracture during the follow-up

84.1 (83.9–84.3)

86.3 (86.1–86.5)

<0.001

Sex

   

 Men

43158 (64.3)

43158 (64.3)

matched

 Women

23914 (35.7)

23914 (35.7)

 

Highest occupational social class before follow-up

  

 Managerial/professional

14072 (21.0)

14454 (21.5)

<0.001

 Office worker

5608 (8.4)

5629 (8.4)

 

 Farming/forestry

12735 (19.0)

13160 (19.6)

 

 Sales/industry/cleaning

28669 (42.7)

26180 (39.0)

 

 Unknown

5470 (8.2)

5186 (7.7)

 

 Did not respond

518 (0.8)

2463 (3.7)

 

Hip replacement

2219 (3.3)

1001 (1.5)

<0.001

Knee replacement

105 (0.2)

67 (0.1)

0.004

Cardiovascular disease

34046 (50.8)

32841 (49.0)

<0.001

Stroke

6356 (9.5)

5232 (7.8)

<0.001

Diabetes

8969 (13.4)

7527 (11.2)

<0.001

Asthma/COPD

5846 (8.7)

6011 (9.0)

0.11

Cancer treatment

792 (1.2)

855 (1.3)

0.12

Any mental or behavioural disorder

15365 (22.9)

5917 (8.8)

<0.001

Any CVD medication

57603 (85.9)

54704 (81.6)

<0.001

Drugs for obstructive airway diseases

15895 (23.7)

15991 (23.8)

0.54

Hormone therapy use

4429 (6.6)

4213 (6.3)

0.16

Bisphosphonates

8932 (13.3)

7460 (11.1)

<0.001

Proton pump inhibitors

22281 (33.2)

21760 (32.4)

0.002

Anti-Parkinson drugs

2349 (3.5)

1959 (2.9)

<0.001

Antiepileptics drugs

6729 (10.0)

5697 (8.5)

<0.001

Antipsychotics

11127 (16.6)

5364 (8.0)

<0.001

Antidepressants

23044 (34.4)

13821 (20.6)

<0.001

Benzodiazepines and related drugs

29368 (43.8)

25915 (38.6)

<0.001

Opioids

28907 (43.1)

25742 (38.4)

<0.001

  1. Data are given as n (%) unless otherwise indicated