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Table 2 Age-related changes of the expression of the selected miRNAs in human peripheral blood mononuclear cells

From: miR-96, miR-145 and miR-9 expression increases, and IGF-1R and FOXO1 expression decreases in peripheral blood mononuclear cells of aging humans

  Expression arbitrary units [median value (25th, 75th percentile)] P-value
miRNA Ya Eb Lc Y vs. E E vs. L Y vs. L
miR-9 0.39 (0.16, 0.82) 0.54 (0.16, 1.13) 0.96 (0.27, 1.40) p = 766 p = 0.381 p = 0.021
miR-96 0.29 (0.10, 0.53) 0.75 (0.22, 2.06) 0.74 (0.23, 2.52) p =0.009 p = 1 p =0.006
miR-99a 2.42 (1.16, 4.83) 1.23 (0.53, 2.59) 1.50 (0.83, 3.41) p =0.038 p = 1 p = 0.265
miR-132 0.21 (0.08, 0.41) 0.21 (0.11, 0.41) 0.25 (0.12, 0.50) p = 1 p = 1 p = 1
miR-145 0.14 (0.07, 0.47) 0.13 (0.06, 0.34) 0.27 (0.13, 0.57) p = 1 p =0.029 p = 0.104
miR-182 0.18 (0.10, 0.47) 0.21 (0.06, 1.02) 0.23 (0.09, 1.55) p = 1 p = 0.752 p = 0.292
  1. a: young (Y), b: elderly (E), c long-lived (L) individuals
  2. Significant p-values are shown in bold