miR-96, miR-145 and miR-9 expression increases, and IGF-1R and FOXO1 expression decreases in peripheral blood mononuclear cells of aging humans

Table 2 Age-related changes of the expression of the selected miRNAs in human peripheral blood mononuclear cells

	Expression arbitrary units [median value (25^th, 75^th percentile)]			P-value
miRNA	Y^a	E^b	L^c	Y vs. E	E vs. L	Y vs. L
miR-9	0.39 (0.16, 0.82)	0.54 (0.16, 1.13)	0.96 (0.27, 1.40)	p = 766	p = 0.381	p = 0.021
miR-96	0.29 (0.10, 0.53)	0.75 (0.22, 2.06)	0.74 (0.23, 2.52)	*p =* 0.009	p = 1	*p =* 0.006
miR-99a	2.42 (1.16, 4.83)	1.23 (0.53, 2.59)	1.50 (0.83, 3.41)	*p =* 0.038	p = 1	p = 0.265
miR-132	0.21 (0.08, 0.41)	0.21 (0.11, 0.41)	0.25 (0.12, 0.50)	p = 1	p = 1	p = 1
miR-145	0.14 (0.07, 0.47)	0.13 (0.06, 0.34)	0.27 (0.13, 0.57)	p = 1	*p =* 0.029	p = 0.104
miR-182	0.18 (0.10, 0.47)	0.21 (0.06, 1.02)	0.23 (0.09, 1.55)	p = 1	p = 0.752	p = 0.292

ISSN: 1471-2318