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Table 1 Patient demographics at baseline for the overall population stratified according to baseline AD dementia severity

From: Resource utilisation, costs and clinical outcomes in non-institutionalised patients with Alzheimer’s disease: 18-month UK results from the GERAS observational study

Characteristic Mild AD dementia(N = 200) Moderate AD dementia (N = 180) MS/S AD dementia (N = 146) Overall (N = 526) P-valuea
Mean age in years [SD] 78.9 [6.7] 78.8 [8.1] 77.6 [8.7] 78.5 [7.8] 0.238
Gender, n female [%] 100 [50.0] 94 [52.2] 91 [62.3] 285 [54.2] 0.061
MMSE score, mean [SD] 23.1 [1.6] 17.8 [1.7] 8.7 [4.5] 17.3 [6.4] N/A
Mean time since diagnosis in years [SD] 1.8 [2.1] 2.0 [1.9] 3.1 [2.2] 2.2 [2.1] <0.001
Caregiver lives with patient, n [%] 156 [78.0] 129 [71.7] 122 [83.6] 407 [77.4] 0.037
Caregiver is spouse, n [%] 144 [72.0] 113 [62.8] 98 [67.1] 355 [67.5] 0.043b
Caregiver mean age in years [SD] 69.4 [11.70] 66.9 [11.77] 68.7 [12.21] 68.3 [11.90] 0.099
Caregiver gender, n female [%] 129 [64.5] 120 [66.7] 76 [52.1] 325 [61.8] 0.016
AD medication use, n [%]      0.012
 No AD medication 31 [15.5] 29 [16.1] 19 [13.1] 79 [15.0]
 Acetylcholinesterase inhibitor monotherapy 167 [83.5] 144 [80.0] 113 [77.9] 424 [80.8]
 Memantine monotherapy 1 [0.5] 5 [2.8] 5 [3.4] 11 [2.1]
 Acetylcholinesterase inhibitor + memantine 1 [0.5] 2 [1.1] 8 [5.5] 11 [2.1]
  1. Percentages are based on the number of respondents (<1.0% missing)
  2. AD Alzheimer’s disease, ANOVA analysis of variance, MMSE Mini-Mental State Examination, MS/S moderately severe/severe, N/A not applicable, SD standard deviation
  3. aANOVA p-value for continuous variables, Cochran–Mantel–Haenszel p-value for categorical variables between AD dementia severity groups
  4. bP-value relates to the relationship of the caregiver to the patient