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Table 2 Univariate and multivariate analyses of toxigenic C. difficile carriage identified by PCR

From: Asymptomatic and yet C. difficile-toxin positive? Prevalence and risk factors of carriers of toxigenic Clostridium difficile among geriatric in-patients

Characteristic

PCR positive

Mean

± standard deviation

PCR negative

Mean

± standard deviation

P value (univariate analysis)

(*significant)

Odds ratio (multivariate analysis)

(95% confidence interval)

Age

80.49 ± 8.93

78.54 ± 7.20

0.123

 

Day of stool sample

(day after admission)

2.58 ± 1.68

2.42 ± 1.64

0.568

 

Length of stay in days

17.14 ± 8.25

16.29 ± 6.41

0.454

 

Number hospital stays

past 6 months

2.07 ± 1.22

1.32 ± 1.00

<0.001*

1.6 times per hospital stay (1.1–2.2)

Length hospital stays

past 6 months

39.88 ± 26.43

22.47 ± 26.39

<0.001*

a

Mini Mental State Examination

25.19 ± 4.99

25.10 ± 5.06

0.920

 

Barthel Index

47.38 ± 23.48

50.86 ± 23.95

0.390

 

Timed Up & Go

27.81 ± 11.57

23,38 ± 10.83

0.084

 

Charlson CM Index

3.91 ± 2.71

3.12 ± 2.25

0.044*

b

Handgrip Strength

36.95 ± 13.68

41.24 ± 16.62

0.123

 

BMI

24.65 ± 6.20

26.22 ± 7.98

0.224

 

Characteristic

PCR positive

Women/Men

PCR negative

Women/Men

P value (univariate analysis)

(*significant)

Odds ratio (multivariate analysis)

(95% confidence interval)

 Sex

65.1%/34.9%

62.3%/37.7%

0.726

 

Characteristic

PCR positive

Yes/No

PCR negative

Yes/No

P value (univariate analysis)

(*significant)

Odds ratio (multivariate analysis)

(95% confidence interval)

 Immunosuppression

14.0%/86.0%

15.6%/84.4%

0.790

 

 Residence care facility

18.6%/81.4%

6.6%/93.4%

0.010*

b

 Previous treatment with antibiotics  past 6 months

93.0%/7.0%

60.8%/39.2%

<0.001*

3.7 times

(1.0–13.9)

 Previous episodes of CDI

11.6%/88.4%

0.9%/99.1%

<0.001*

12.3 times

(1.9–81.6)

 PPI premedication

76.7%/23.3%

62.3%/37.7%

0.071

 

 “Post–Sugery” hospital stay

53.5%/46.5%

21.2%/78.8%

<0.001*

3.5 times

(1.4–8.8)

  1. alength of hospital stay correlated by R = 0.58 to the variable “number of hospital stays” and was therefore excluded from the final multivariate model
  2. bnot statistically significant in the multivariate model