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Table 2 Univariate and multivariate analyses of toxigenic C. difficile carriage identified by PCR

From: Asymptomatic and yet C. difficile-toxin positive? Prevalence and risk factors of carriers of toxigenic Clostridium difficile among geriatric in-patients

Characteristic PCR positive
Mean
± standard deviation
PCR negative
Mean
± standard deviation
P value (univariate analysis)
(*significant)
Odds ratio (multivariate analysis)
(95% confidence interval)
Age 80.49 ± 8.93 78.54 ± 7.20 0.123  
Day of stool sample
(day after admission)
2.58 ± 1.68 2.42 ± 1.64 0.568  
Length of stay in days 17.14 ± 8.25 16.29 ± 6.41 0.454  
Number hospital stays
past 6 months
2.07 ± 1.22 1.32 ± 1.00 <0.001* 1.6 times per hospital stay (1.1–2.2)
Length hospital stays
past 6 months
39.88 ± 26.43 22.47 ± 26.39 <0.001* a
Mini Mental State Examination 25.19 ± 4.99 25.10 ± 5.06 0.920  
Barthel Index 47.38 ± 23.48 50.86 ± 23.95 0.390  
Timed Up & Go 27.81 ± 11.57 23,38 ± 10.83 0.084  
Charlson CM Index 3.91 ± 2.71 3.12 ± 2.25 0.044* b
Handgrip Strength 36.95 ± 13.68 41.24 ± 16.62 0.123  
BMI 24.65 ± 6.20 26.22 ± 7.98 0.224  
Characteristic PCR positive
Women/Men
PCR negative
Women/Men
P value (univariate analysis)
(*significant)
Odds ratio (multivariate analysis)
(95% confidence interval)
 Sex 65.1%/34.9% 62.3%/37.7% 0.726  
Characteristic PCR positive
Yes/No
PCR negative
Yes/No
P value (univariate analysis)
(*significant)
Odds ratio (multivariate analysis)
(95% confidence interval)
 Immunosuppression 14.0%/86.0% 15.6%/84.4% 0.790  
 Residence care facility 18.6%/81.4% 6.6%/93.4% 0.010* b
 Previous treatment with antibiotics  past 6 months 93.0%/7.0% 60.8%/39.2% <0.001* 3.7 times
(1.0–13.9)
 Previous episodes of CDI 11.6%/88.4% 0.9%/99.1% <0.001* 12.3 times
(1.9–81.6)
 PPI premedication 76.7%/23.3% 62.3%/37.7% 0.071  
 “Post–Sugery” hospital stay 53.5%/46.5% 21.2%/78.8% <0.001* 3.5 times
(1.4–8.8)
  1. alength of hospital stay correlated by R = 0.58 to the variable “number of hospital stays” and was therefore excluded from the final multivariate model
  2. bnot statistically significant in the multivariate model