From: Quinine induced simvastatin toxicity through cytochrome inhibition - a case report
Age | 87 years |
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Symptoms | Nocturnal leg cramps of moderate intensity since years. Since three weeks intensity of symptoms increased despite the use of quinine for symptomatic relief |
Medical history | myocardial infarction in 2002 with consecutive coronary artery bypass graft (CABG) arterial hypertension chronic kidney disease III knee replacement left + right. |
Medication | aspirin 100 mg 1-0-0 bisoprolol 2,5 mg 1-0-0 ramipril 5 mg 1-0-0 simvastatin 40 mg 0-0-1 vitamin D3 1000 IU 1-0-0 torasemide 5 mg 1-0-0 fentanyl patch 12,5 μg once every 3 days. Self-medication: quinine200 mg once daily |