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Table 2 Acute clinical and radiological status, post-stroke outcome and stroke mechanisms

From: The impact of intravenous thrombolysis on outcome of patients with acute ischemic stroke after 90 years old

  Thrombolysed Non-thrombolysed p
N = 37 N = 41
Acute clinical status, mean (SD)    
 NIHSS at baseline 16 (7) 13 (6) 0.06
 NIHSS at 24 h 15 (8) 12 (7) NS
 Systolic blood pressure (mmHg) 151 (28) 164 (25) 0.03
 Diastolic blood pressure (mmHg) 79 (18) 85 (22) NS
 Temperature (Celsius degree) 36.4 (0.6) 36.6 (0.6) NS
 Capillary blood glucose level (g/L) 1.2 (0.3) 1.2 (0.4) NS
Onset to needle time, mean (SD) 168 min (48) - -
 Imaging parameters    
  Mismatch, n (%) 30 (81) - -
  Non-contrast CT ASPECTS, mean (SD) 8.3 (2.2) 8.4 (3.3) NS
  Intracranial occlusion, n (%) 27 (73) 14 (34) 0.002
   M1 12 (45) 7 (50) NS
   M2 10 (37) 3 (22) 0.02
   M3 2 (7) 1 (7) NS
   ACA 1 (4) 1 (7) NS
   PCA 2 (7) 1 (7) NS
   VB 0 1 (7) NS
  Microbleeds, n (%) (n = 25) (n = 24)  
   1 – 5 6 (24) 6 (25) NS
   >5 1 (4) 0 NS
 Post-stroke complications, n (%)    
  Delirium 11 (30) 3 (7) 0.01
  Mood disorder 3 (8) 2 (5) NS
  Swallowing disorder 14 (38) 4 (10) 0.003
  Seizure 0 1 (2) NS
  Ischemic heart attack 1 (3) 3 (7) NS
  Pulmonary infection 12 (32) 6 (15) NS
  Urinary infection 3 (8) 1 (2) NS
 Hemorrhagic transformation, n (%) 20 (54) 5 (12) 0.002
  HI 1 and 2 8 (40) 4 (80) NS
  PH 1 and 2 12 (60) 1 (20) 0.003
 Symptomatic intracranial hemorrhage, n (%) 8 (22) 0 0.08
 Duration of hospitalization, mean (SD) 10 days (12) 7 days (9) 0.046
 mRS 0–2 at 3 months, n (%) 2 (5) 3 (7) NS
 Post-stroke outcome, n (%)    
  Death ≤ 7 days 8 (22) 4 (10) NS
  Death > 7 days 6 (16) 6 (15) NS
  Return to home 5 (14) 7 (17) NS
  Rehabilitation center 10 (39) 7 (17) NS
  Other medical department 8 (22) 15 (37) NS
  Nursing home 3 (8) 10 (24) NS
 Stroke subtypes (TOAST), n (%)    
  Large artery atherosclerosis 3 (8) 10 (24) NS
  Cardioembolic (AF) 27 (73) 24 (59) NS
  Small vessel disease 0 0 -
  Other 0 1 (2) NS
  Undetermined 7 (19) 6 (15) NS
  1. NIHSS National Institute of Health Stroke Scale, ASPECTS Alberta Stroke Program Early CT score, M1 - M2 - M3 segments of middle cerebral artery, ACA anterior cerebral artery, PCA posterior cerebral artery, VB vertebral-basilar arteries, HI hemorrhagic infarction, PH, parenchymal hemorrhage, AF atrial fibrillation, NS non-significant