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Table 2 Acute clinical and radiological status, post-stroke outcome and stroke mechanisms

From: The impact of intravenous thrombolysis on outcome of patients with acute ischemic stroke after 90 years old

 

Thrombolysed

Non-thrombolysed

p

N = 37

N = 41

Acute clinical status, mean (SD)

   

 NIHSS at baseline

16 (7)

13 (6)

0.06

 NIHSS at 24 h

15 (8)

12 (7)

NS

 Systolic blood pressure (mmHg)

151 (28)

164 (25)

0.03

 Diastolic blood pressure (mmHg)

79 (18)

85 (22)

NS

 Temperature (Celsius degree)

36.4 (0.6)

36.6 (0.6)

NS

 Capillary blood glucose level (g/L)

1.2 (0.3)

1.2 (0.4)

NS

Onset to needle time, mean (SD)

168 min (48)

-

-

 Imaging parameters

   

  Mismatch, n (%)

30 (81)

-

-

  Non-contrast CT ASPECTS, mean (SD)

8.3 (2.2)

8.4 (3.3)

NS

  Intracranial occlusion, n (%)

27 (73)

14 (34)

0.002

   M1

12 (45)

7 (50)

NS

   M2

10 (37)

3 (22)

0.02

   M3

2 (7)

1 (7)

NS

   ACA

1 (4)

1 (7)

NS

   PCA

2 (7)

1 (7)

NS

   VB

0

1 (7)

NS

  Microbleeds, n (%)

(n = 25)

(n = 24)

 

   1 – 5

6 (24)

6 (25)

NS

   >5

1 (4)

0

NS

 Post-stroke complications, n (%)

   

  Delirium

11 (30)

3 (7)

0.01

  Mood disorder

3 (8)

2 (5)

NS

  Swallowing disorder

14 (38)

4 (10)

0.003

  Seizure

0

1 (2)

NS

  Ischemic heart attack

1 (3)

3 (7)

NS

  Pulmonary infection

12 (32)

6 (15)

NS

  Urinary infection

3 (8)

1 (2)

NS

 Hemorrhagic transformation, n (%)

20 (54)

5 (12)

0.002

  HI 1 and 2

8 (40)

4 (80)

NS

  PH 1 and 2

12 (60)

1 (20)

0.003

 Symptomatic intracranial hemorrhage, n (%)

8 (22)

0

0.08

 Duration of hospitalization, mean (SD)

10 days (12)

7 days (9)

0.046

 mRS 0–2 at 3 months, n (%)

2 (5)

3 (7)

NS

 Post-stroke outcome, n (%)

   

  Death ≤ 7 days

8 (22)

4 (10)

NS

  Death > 7 days

6 (16)

6 (15)

NS

  Return to home

5 (14)

7 (17)

NS

  Rehabilitation center

10 (39)

7 (17)

NS

  Other medical department

8 (22)

15 (37)

NS

  Nursing home

3 (8)

10 (24)

NS

 Stroke subtypes (TOAST), n (%)

   

  Large artery atherosclerosis

3 (8)

10 (24)

NS

  Cardioembolic (AF)

27 (73)

24 (59)

NS

  Small vessel disease

0

0

-

  Other

0

1 (2)

NS

  Undetermined

7 (19)

6 (15)

NS

  1. NIHSS National Institute of Health Stroke Scale, ASPECTS Alberta Stroke Program Early CT score, M1 - M2 - M3 segments of middle cerebral artery, ACA anterior cerebral artery, PCA posterior cerebral artery, VB vertebral-basilar arteries, HI hemorrhagic infarction, PH, parenchymal hemorrhage, AF atrial fibrillation, NS non-significant