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Increased CSF levels of aromatic amino acids in hip fracture patients with delirium suggests higher monoaminergic activity

  • Leiv Otto Watne1, 2, 3, 4Email author,
  • Ane-Victoria Idland1, 2,
  • Durk Fekkes5,
  • Johan Raeder1, 6,
  • Frede Frihagen7,
  • Anette Hylen Ranhoff8, 9,
  • Farrukh Abbas Chaudhry3,
  • Knut Engedal1, 10,
  • Torgeir Bruun Wyller1, 2 and
  • Bjørnar Hassel11, 12Email author
BMC GeriatricsBMC series – open, inclusive and trusted201616:149

Received: 1 April 2016

Accepted: 28 July 2016

Published: 2 August 2016

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Open Peer Review reports

Pre-publication versions of this article and author comments to reviewers are available by contacting

Original Submission
1 Apr 2016 Submitted Original manuscript
Author responded Author comments
Reviewed Reviewer Report
Resubmission - Version 2
Submitted Manuscript version 2
Author responded Author comments
Resubmission - Version 3
Submitted Manuscript version 3
28 Jul 2016 Editorially accepted
2 Aug 2016 Article published 10.1186/s12877-016-0324-0

How does Open Peer Review work?

Open peer review is a system where authors know who the reviewers are, and the reviewers know who the authors are. If the manuscript is accepted, the named reviewer reports are published alongside the article. Pre-publication versions of the article and author comments to reviewers are available by contacting All previous versions of the manuscript and all author responses to the reviewers are also available.

You can find further information about the peer review system here.

Authors’ Affiliations

Institute of Clinical Medicine, University of Oslo
Oslo Delirium Research Group, Department of Geriatric Medicine, Oslo University Hospital
Institute of Basic Medical Sciences, University of Oslo
Edinburgh Delirium Research Group, Geriatric Medicine, University of Edinburgh
Department of Clinical Chemistry, Erasmus MC, University Medical Center Rotterdam
Department of Anesthesiology, Oslo University Hospital
Department of Orthopaedic Surgery, Oslo University Hospital
Department of Medicine, Diakonhjemmet Hospital
Department of Clinical Science, University of Bergen
Norwegian National Advisory Unit on Ageing and Health, Vestfold Health Trust
Department of Complex Neurology and Neurohabilitation, Oslo University Hospital
Norwegian Defense Research Establishment (FFI)