Association of pre-operative medication use with post-operative delirium in surgical oncology patients receiving comprehensive geriatric assessment

Table 3 Univariate and multivariate regression analyses to identify predictors for post-operative delirium

Characteristics	Unadjusted OR (95 % CI)	Adjusted OR (95 % CI)	Adjusted OR (95 % CI)
Characteristics	Unadjusted OR (95 % CI)	Model I	Model II
Age	1.117 (1.029–1.212)^**	1.098 (1.005–1.199)^*	1.098 (1.006–1.199)^*
Male	2.137 (0.826–5.526)	2.776 (1.029–7.490)^*	2.921 (1.056–8.081)^*
BMI	0.868 (0.752–1.002)
CVD	1.463 (0.477–4.493)
Diabetes Mellitus	1.000 (0.353–2.835)
Dementia	5.906 (1.542–22.675)^**	2.135 (0.507–8.998)	3.860 (0.886–16.806)
CrCl < 50 mL/min	1.446 (0.413–5.069)
GI Cancer	3.036 (0.691–13.335)
Delirium Risk Score ≥2	3.955 (0.826–18.925)
Polypharmacy	2.186 (0.817–5.851)
PDRM	1.027 (0.406–2.602)
DIM	12.680 (2.895–55.541)^***	12.775 (2.826–57.741)^***
FIM	5.654 (0.746–42.843)
PIM	5.083 (1.955–13.220)^***		5.525 (2.028–15.054)^***

For model I construction, age, sex, dementia, and DIM were included for analysis. For model II construction, age, sex, dementia, and PIM were included for analysis
BMI body mass index, CVD cardiovascular disease, CrCl creatinine clearance, PDRM pre-operative discontinuation requiring medication, DIM delirium-inducing medication, FIM fall-inducing medication, PIM potentially inappropriate medication
^*P < 0.05, ^**P < 0.01, ^***P < 0.001

ISSN: 1471-2318