From: Assessing the economic burden of Alzheimer’s disease patients first diagnosed by specialists
Selected Characteristics | Before Matching | After Matching | ||||
---|---|---|---|---|---|---|
Specialist (n = 2593) | No Specialist (n = 13,961) | p-Value* | Specialist (n = 2503) | No Specialist (n = 2503) | p-Value** | |
Age on index date, mean (SD) | 78.8 (8.7) | 80.8 (8.2) | <0.0001 | 79.1 (8.3) | 79.3 (8.1) | 0.3593 |
% male | 40 % | 34 % | <0.0001 | 40 % | 39 % | 0.4781 |
Charlson Comorbidity Index, mean (SD) | 2.2 (2.2) | 1.9 (2.1) | <0.0001 | 2.1 (2.1) | 2.1 (2.1) | 0.5307 |
Comorbidities, % | ||||||
Chronic obstructive pulmonary disease | 18 % | 17 % | 0.8061 | 17 % | 18 % | 0.2465 |
Depression | 20 % | 18 % | 0.0890 | 19 % | 20 % | 0.4097 |
Diabetes | 31 % | 29 % | 0.1159 | 30 % | 33 % | 0.0123 |
Epilepsy | 4 % | 2 % | <0.0001 | 3 % | 2 % | 0.0080 |
Hyperlipidemia | 62 % | 52 % | <0.0001 | 61 % | 63 % | 0.1431 |
Hypertension | 78 % | 76 % | 0.0270 | 77 % | 80 % | 0.0059 |
Ischemic heart disease | 37 % | 31 % | <0.0001 | 36 % | 35 % | 0.1537 |
Other cardiovascular conditions | 60 % | 55 % | <0.0001 | 59 % | 58 % | 0.4371 |
Stroke/cerebrovascular disease | 28 % | 20 % | <0.0001 | 27 % | 20 % | <0.0001 |
Urinary tract infection | 22 % | 21 % | 0.7036 | 21 % | 23 % | 0.0579 |
Time to AD diagnosis, mean (SD) | 3.6 (6.2) | 4.9 (7.2) | <0.0001 | 3.5 (6.2) | 4.6 (6.8) | <0.0001 |
Months of follow-up, mean (SD) | 29.8 (9.8) | 31.2 (10.2) | <0.0001 | 29.9 (9.8) | 30.1 (10.0) | 0.0105 |
Total healthcare costs, mean (SD)a | $15,058 ($26,139) | $13,339 ($24,356) | <0.0001 | $12,497 ($18,789) | $12,503 ($18,797) | 0.5597 |