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Table 1 Comparison of baseline characteristics and clinical outcome 12 months after acute hospitalization

From: Readmission and mortality one year after acute hospitalization in older patients with explained and unexplained anemia - a prospective observational cohort study

 

Total sample

No anemia

Anemia

 

N=884

474 (54%)

410 (46%)

Demographics

   

Age

84 (6.2)

84 (6.2)

85 (6.2)

Male

284

119 (42%)

165 (58%)**

Women

600

355 (59%)

245 (41%)

Receive home care

362 (40%)

196 (42%)

166 (38%)

Admitted after a fall

367 (41%)

137 (38%)

190 (44%)

Admission diagnosis

   

Hip fracture

66 (8%)

15 (3%)

51 (12%)**

Other acute trauma

258 (29%)

144 (30%)

114 (28%)

Infection

218 (25%)

116 (25%)

102 (25%)

Heart diseasee

133 (15%)

68 (14%)

65 (16%)

Other medical/pulmonary diseases

209 (23%)

131 (28%)

78 (19%)

Geriatric assessment

   

More than 5 diagnosis

528 (63%)

266 (56%)

262 (64%)**

Use > 5 drugs

705 (81%)

361 (76%)

344 (84%)*

Barthel index

75 (60-85)

80 (60-90)

75 (60-85)**

Depression, GDS

7 (4-12)

7 (4-12)

7 (3-12)

Cognition, MMSE

26 (23-28)

26 (23-28)

26 (23-28)

Nutrition, MNA-SF

10 (8-12)

10 (8-12)

10 (8-12)

Laboratory assessments

   

Hb, g/dL

12.3 (7.6-19.0)

13.4 (12.0-19.0)

11.0 (7.6-12.9)**

Hb men, g/dL

12.4 (7.6-19.0)

13.8 (13.0-19.0)

11.3 (7.6-12.9)**

Hb women, g/dL

12.3 (8.6-18.0)

13.2 (12.0-18.0

11.0 (8.6-11.9)**

Severe anemi (<10.6g/L)a

130 (15%)

0

130 (32%)**

MCVfL

94 (6)

94 (6)

94 (6)

VitB12, pmol/L

506 (331-780)

471 (319 -772)

574 (361-826)**

Folate, nmol/L

16.2 (5.3-45..0)

13.2 (5.0-45.3)

14.8 (5.0-45.3)

Ferritin µg/L

184 (104-350)

179 (101-333)

193 (107-366)

Transferrin receptor, ml/L

3.4 (2.7-4.4)

3.3 (2.7-4.2)

3.4 (2.7-4.6)

CRP, mg/L

18 (1-331)

13 (1-217)

27 (1-331)**

Renal insufficiencyb

362 (41%)

157 (34%)

205 (50%)**

NT pro-BnP, pmol/L

92 (35-266)

69 (28-188)

134 (45-377)**

1 year follow up

   

>2 hospital admissions

229 (33%)

144 (31%)

15 (35%)

Dead

150 (17%)

74 (16%)

77 (19%)

  1. Continuous parameters are presented as mean (standard deviation) and median (interquartile range), categorical data are presented as numbers (percentages)
  2. GDS Geriatric Depression scale, range 1-30, MMSE Mini Mental Status Examination, MNA-SF Mini Nutritional Assessment- Short Form, CRP C-reactive protein, NT pro- BnP N-Terminal pro brain-type natriuretic peptide, Hb Hemoglobin, MCV mean corposcular volume.
  3. *p<0.05, **p<0.01 when the group of non-anemic and anemic patients were compared.
  4. aSevere anemia defined as Hb concentration in the lower anemia tertile.
  5. Renal insufficiency was defined as e-GFR (described in methods) < 60 mL/min/1.73 m2.