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Candidate gene resequencing to identify rare, pedigree-specific variants influencing healthy aging phenotypes in the long life family study

  • Todd E. Druley1, 2,
  • Lihua Wang1, 3,
  • Shiow J. Lin1, 3,
  • Joseph H. Lee4, 5, 6,
  • Qunyuan Zhang1, 3,
  • E. Warwick Daw1, 3,
  • Haley J. Abel1, 3,
  • Sara E. Chasnoff1, 2,
  • Enrique I. Ramos1, 2,
  • Benjamin T. Levinson1, 2,
  • Bharat Thyagarajan7,
  • Anne B. Newman8,
  • Kaare Christensen9,
  • Richard Mayeux10 and
  • Michael A. Province1, 3Email author
BMC GeriatricsBMC series – open, inclusive and trusted201616:80

https://doi.org/10.1186/s12877-016-0253-y

Received: 7 May 2015

Accepted: 4 April 2016

Published: 9 April 2016

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Open Peer Review reports

Pre-publication versions of this article and author comments to reviewers are available by contacting info@biomedcentral.com.

Original Submission
7 May 2015 Submitted Original manuscript
Author responded Author comments
Resubmission - Version 2
Submitted Manuscript version 2
Author responded Author comments
Reviewed Reviewer Report
Reviewed Reviewer Report
Reviewed Reviewer Report
Resubmission - Version 3
Submitted Manuscript version 3
Author responded Author comments
Resubmission - Version 4
Submitted Manuscript version 4
Author responded Author comments
Reviewed Reviewer Report
Reviewed Reviewer Report
Resubmission - Version 5
Submitted Manuscript version 5
Author responded Author comments
Resubmission - Version 6
Submitted Manuscript version 6
Publishing
4 Apr 2016 Editorially accepted
9 Apr 2016 Article published 10.1186/s12877-016-0253-y

How does Open Peer Review work?

Open peer review is a system where authors know who the reviewers are, and the reviewers know who the authors are. If the manuscript is accepted, the named reviewer reports are published alongside the article. Pre-publication versions of the article and author comments to reviewers are available by contacting info@biomedcentral.com. All previous versions of the manuscript and all author responses to the reviewers are also available.

You can find further information about the peer review system here.

Authors’ Affiliations

(1)
Center for Genome Sciences and Systems Biology, Washington University School of Medicine
(2)
Department of Pediatrics, Washington University School of Medicine
(3)
Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine
(4)
Sergievsky Center, College of Physicians and Surgeons, Columbia University New York
(5)
Taub Institute, College of Physicians and Surgeons, Columbia University New York
(6)
Department of Epidemiology, School of Public Health, Columbia University New York
(7)
Department of Laboratory Medicine and Pathology, University of Minnesota
(8)
Department of Epidemiology, University of Pittsburgh Graduate School of Public Health
(9)
The Danish Aging Research Center, Epidemiology, University of Southern Denmark
(10)
Gertrude H. Sergievsky Center and the Taub Institute for Research on Alzheimer’s Disease and the Aging Brain, Columbia University

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