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Table 3 Estimate of the effect of klotho G-392A polymorphism on MetS and its components with logistic regression

From: The Klotho gene G-395A polymorphism and metabolic syndrome in very elderly people

  MetS Components of MetS
Abdominal obesity Hypertriglyceridemia Low HDL-C High BP High FPG
Total
GG genotype, ORa (95 % CI) 1 (reference) 1 (reference) 1 (reference) 1 (reference) 1 (reference) 1 (reference)
GA + AA genotype, ORa (95 % CI) 0.50 (0.25, 0.98) 0.95 (0.60, 1.49) 0.66 (0.39, 0.95) 0.84 (0.51, 1.37) 0.48 (0.34, 0.67) 1.47 (0.93, 2.31)
Men
GG genotype, ORb (95 % CI) 1 (reference) 1 (reference) 1 (reference) 1 (reference) 1 (reference) 1 (reference)
GA + AA genotype, ORb (95 % CI) 0.42 (0.05, 3.85) 0.36 (0.16, 1.89) 1.66 (0.47, 5.80) 0.69 (0.27, 0.93) 0.47 (0.25, 0.90) 1.00 (0.47, 2.12)
Women
GG genotype, ORb (95 % CI) 1 (reference) 1 (reference) 1 (reference) 1 (reference) 1 (reference) 1 (reference)
GA + AA genotype, ORb (95 % CI) 0.51 (0.24, 0.97) 1.06 (0.66, 1.71) 0.54 (0.31, 0.98) 0.99 (0.58, 1.68) 0.47 (0.31, 0.71) 1.93 (0.96, 3.51)
  1. Abbreviations: BMI body mass index, BP blood pressure, FPG fasting plasma glucose, HDL-C high density lipoprotein cholesterol, MetS metabolic syndrome, SUA serum uric acid
  2. aAdjusted for age, gender, smoking habits, alcohol habits, exercise habits, BMI, and SUA
  3. bAdjusted for age, smoking habits, alcohol habits, exercise habits, BMI and SUA