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Table 2 Characteristics of subjects according to the klotho G-395A polymorphism (N = 695)

From: The Klotho gene G-395A polymorphism and metabolic syndrome in very elderly people

Characteristics

Total (N = 695)

Men (N = 220)

Women (N = 475)

GG genotype (N = 490)

GA + AA genotype (N = 205)

P

GG genotype (N = 161)

GA + AA genotype (N = 59)

P

GG genotype (N = 329)

GA + AA genotype (N = 146)

P

Age (years)

93.6 ± 3.3

93.2 ± 2.9

0.074

93.4 ± 3.2

93.2 ± 3.0

0.679

93.8 ± 3.4

93.2 ± 2.9

0.073

Women (%)

67.1

71.2

0.292

-

-

-

-

-

-

BMI (kg/m2)

19.2 ± 3.8

19.4 ± 3.3

0.727

19.6 ± 4.1

20.0 ± 3.1

0.505

19.1 ± 3.6

19.1 ± 3.4

0.952

Smoking habits*

45.0

37.9

0.089

71.2

67.2

0.568

32.1

26.2

0.198

Alcohol habits**

25.5

27.2

0.645

42.1

29.3

0.086

17.4

26.4

0.026

Exercise habits***

41.2

39.3

0.652

42.0

39.7

0.753

40.7

39.2

0.748

SUA (mmol/L)

318.8 ± 87.5

318.7 ± 89.9

0.998

346.1 ± 81.3

369.3 ± 98.6

0.079

305.5 ± 87.4

298.2 ± 77.5

0.387

MetS (%)

10.8

5.9

0.040

3.7

1.7

0.447

14.3

7.5

0.038

Components of MetS

Abdominal obesity (%)

25.5

26.3

0.819

9.3

5.1

0.310

33.4

34.9

0.750

Hypertriglyceridemia (%)

19.2

11.7

0.017

10.2

5.6

0.233

20.7

12.3

0.029

Low HDL-C (%)

16.1

14.1

0.623

9.9

1.7

0.043

19.2

19.7

0.894

High BP (%)

66.3

49.8

<0.001

62.1

45.8

0.030

68.4

51.4

<0.001

High FPG (%)

13.7

17.6

0.188

20.5

22.0

0.804

10.3

15.8

0.094

  1. Abbreviations: BMI body mass index, BP blood pressure, FPG fasting plasma glucose, HDL-C high density lipoprotein cholesterol, MetS metabolic syndrome, SUA serum uric acid
  2. *Indicates those who were a smoker at the time of the interview
  3. **Indicates those who still drank alcohol at least once a day at the time of the interview
  4. ***Indicates those who still did some physical exercise at least 3 time per week at the time of the interview