From: The Klotho gene G-395A polymorphism and metabolic syndrome in very elderly people
Characteristics | Total (N = 695) | Men (N = 220) | Women (N = 475) | ||||||
---|---|---|---|---|---|---|---|---|---|
GG genotype (N = 490) | GA + AA genotype (N = 205) | P | GG genotype (N = 161) | GA + AA genotype (N = 59) | P | GG genotype (N = 329) | GA + AA genotype (N = 146) | P | |
Age (years) | 93.6 ± 3.3 | 93.2 ± 2.9 | 0.074 | 93.4 ± 3.2 | 93.2 ± 3.0 | 0.679 | 93.8 ± 3.4 | 93.2 ± 2.9 | 0.073 |
Women (%) | 67.1 | 71.2 | 0.292 | - | - | - | - | - | - |
BMI (kg/m2) | 19.2 ± 3.8 | 19.4 ± 3.3 | 0.727 | 19.6 ± 4.1 | 20.0 ± 3.1 | 0.505 | 19.1 ± 3.6 | 19.1 ± 3.4 | 0.952 |
Smoking habits* | 45.0 | 37.9 | 0.089 | 71.2 | 67.2 | 0.568 | 32.1 | 26.2 | 0.198 |
Alcohol habits** | 25.5 | 27.2 | 0.645 | 42.1 | 29.3 | 0.086 | 17.4 | 26.4 | 0.026 |
Exercise habits*** | 41.2 | 39.3 | 0.652 | 42.0 | 39.7 | 0.753 | 40.7 | 39.2 | 0.748 |
SUA (mmol/L) | 318.8 ± 87.5 | 318.7 ± 89.9 | 0.998 | 346.1 ± 81.3 | 369.3 ± 98.6 | 0.079 | 305.5 ± 87.4 | 298.2 ± 77.5 | 0.387 |
MetS (%) | 10.8 | 5.9 | 0.040 | 3.7 | 1.7 | 0.447 | 14.3 | 7.5 | 0.038 |
Components of MetS | |||||||||
Abdominal obesity (%) | 25.5 | 26.3 | 0.819 | 9.3 | 5.1 | 0.310 | 33.4 | 34.9 | 0.750 |
Hypertriglyceridemia (%) | 19.2 | 11.7 | 0.017 | 10.2 | 5.6 | 0.233 | 20.7 | 12.3 | 0.029 |
Low HDL-C (%) | 16.1 | 14.1 | 0.623 | 9.9 | 1.7 | 0.043 | 19.2 | 19.7 | 0.894 |
High BP (%) | 66.3 | 49.8 | <0.001 | 62.1 | 45.8 | 0.030 | 68.4 | 51.4 | <0.001 |
High FPG (%) | 13.7 | 17.6 | 0.188 | 20.5 | 22.0 | 0.804 | 10.3 | 15.8 | 0.094 |