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Table 4 Characteristics of study population between uric acid reducing group and uric acid increasing group

From: Influence of changes in serum uric acid levels on renal function in elderly patients with hypertension: a retrospective cohort study with 3.5-year follow-up

  Uric acid reduced group (n = 399) Uric acid increased group (n = 391)
  Baseline At 3 years P Baseline At 3 years P
Age (years) 68.2 ± 10.5 71.7 ± 10.5 <0.001 70.0 ± 9.5 73.7 ± 9.6 <0.001
Men (n, %) 211 (52.9) - - 206 (52.7) - -
Hypertension duration (years) 9.2 ± 8.4 - - 11.4 ± 9.6 - -
Diabetes (n, %) 110 (27.6) 131 (32.8) 0.001 131 (33.5) 153 (39.1) <0.001
Body mass index (kg/m2) 24.59 ± 3.34 24.26 ± 3.61 0.009 25.11 ± 3.87 25.18 ± 4.04 0.558
Administration of statins (n, %) 321 (80.5) 384 (96.2) <0.001 336 (85.9) 353 (90.3) 0.006
Antihypertensive therapeutic intensity score 0.94 ± 0.84 0.81 ± 0.62 0.003 0.95 ± 0.85 0.84 ± 0.63 0.020
Systolic blood pressure (mmHg) 145.43 ± 18.56 141.50 ± 19.36 0.003 131.96 ± 14.88 135.66 ± 17.20 0.001
Diastolic blood pressure (mmHg) 80.32 ± 13.30 77.49 ± 12.14 <0.001 73.83 ± 7.89 72.73 ± 11.46 0.101
Pressure-target rate (n, %) 122 (30.6) 167 (41.9) <0.001 257 (65.7) 139 (35.6) 0.001
Fasting blood glucose (mmol/L) 5.70 ± 1.64 6.11 ± 1.92 <0.001 5.87 ± 1.73 6.05 ± 1.72 0.044
Triacylglycerol (mmol/L) 1.72 ± 1.07 1.48 ± 0.93 <0.001 1.65 ± 1.28 1.63 ± 1.05 0.792
Total cholesterol (mmol/L) 4.94 ± 1.15 4.58 ± 1.28 <0.001 4.81 ± 2.31 4.64 ± 1.22 0.143
HDL-C (mmol/L) 1.22 ± 0.35 1.20 ± 0.42 0.264 1.20 ± 0.44 1.17 ± 0.37 0.186
LDL-C (mmol/L) 3.02 ± 1.08 2.85 ± 1.06 0.010 2.80 ± 0.93 2.89 ± 1.00 0.094
Uric acid (μmol/L) 380.88 ± 100.04 301.19 ± 86.95 <0.001 318.62 ± 94.68 402.20 ± 116.64 <0.001
eGFR (ml/min per 1.73 m2) 73.36 ± 29.61 72.33 ± 27.01 0.539 74.51 ± 26.87 66.24 ± 28.25 <0.001
  1. Note: eGFR estimated glomerular filtration rate, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein-cholesterol. Blood pressure was calculated as the average of blood pressure on admission and at discharge