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Table 1 Clinical characteristics between subjects with hyperuricemia and with normal uric acid at baseline

From: Influence of changes in serum uric acid levels on renal function in elderly patients with hypertension: a retrospective cohort study with 3.5-year follow-up

  Normal uric acid (n = 609) Hyperuricemia (n = 256) P
Age (years) 68.96 ± 10.01 68.95 ± 10.44 0.996
Men (n, %) 313 (49.87 %) 142 (47.41 %) 0.294
Hypertension duration (years) 10.8 ± 8.1 9.0 ± 7.3 0.301
Diabetes(n, %) 186 (25.06 %) 77 (25.93 %) 0.892
chronic kidney disease (n, %) 151 (38.23 %) 240 (24.90 %) <0.001
Body mass index (kg/m2) 24.43 ± 3.50 25.43 ± 3.66 <0.001
Antihypertensive therapeutic intensity score 0.89 ± 0.79 1.06 ± 0.88 0.010
Systolic blood pressure (mmHg) 145.79 ± 18.52 146.79 ± 20.58 0.484
Diastolic blood pressure (mmHg) 79.52 ± 12.57 80.75 ± 13.09 0.198
Fasting blood glucose (mmol/L) 5.84 ± 1.73 5.63 ± 1.42 0.066
Triacylglycerol (mmol/L) 1.58 ± 1.17 1.92 ± 1.18 <0.001
Total cholesterol (mmol/L) 4.80 ± 1.92 5.06 ± 1.30 0.061
HDL-C (mmol/L) 1.22 ± 0.41 1.17 ± 0.35 0.092
LDL-C (mmol/L) 2.85 ± 0.94 3.09 ± 1.16 0.007
Uric acid (umol/L) 298.66 ± 67.17 466.23 ± 66.61 <0.001
eGFR (ml/min/1.73 m2) 76.91 ± 28.76 68.95 ± 10.44 0.001
  1. Note: 1 mmHg = 0.333 kPa; HDL-C: high-density lipoprotein-cholesterol; LDL-C: low-density lipoprotein-cholesterol; eGFR: estimated glomerular filtration rate