Any versus long-term prescribing of high risk medications in older people using 2012 Beers Criteria: results from three cross-sectional samples of primary care records for 2003/4, 2007/8 and 2011/12

Table 3 Logistic regression models for long-term HRM prescribing

	Model 1		Model 2		Model 3
Sample size (unweighted)^a	12,532		12,532		12,532
	Weighted OR (95 % CI)	p-value	Weighted OR (95 % CI)	p-value	Weighted OR (95 % CI)	p-value
Year sampled
2003/4	1		1		1
2007/8	0.82 (0.70, 0.96)	0.015	0.73 (0.61, 0.85)	<0.001	0.73 (0.62, 0.86)	<0.001
2011/12	0.74 (0.63, 0.87)	0.000	0.61 (0.51, 0.71)	<0.001	0.61 (0.51, 0.72)	<0.001
Age
65 to 84 years	1		1		1
85 years or over	1.26 (1.13, 1.39)	0.000	1.15 (1.03, 1.28)	0.009	1.16 (1.04, 1.28)	0.007
Sex
Men			1		1
Women	1.35 (1.17, 1.56)	0.000	1.40 (1.20, 1.62)	<0.001	1.41 (1.20, 1.63)	<0.001
Medications count (number of drugs)
1			1		1
2 to 4			2.27 (1.75, 2.93)	<0.001	2.46 (1.91, 3.16)	<0.001
5 to 9			4.71 (3.62, 6.12)	<0.001	5.33 (4.08, 6.94)	<0.001
10 or more			15.44 (10.0, 23.7)	<0.001	17.77 (11.4, 27.5)	<0.001
None					1
1 to 2					0.66 (0.49, 0.86)	0.003
3 or more					0.62 (0.46, 0.83)	0.001
Socio-economic status (IMD^b quintiles)
Least deprived					1
2nd					1.11 (0.87, 1.41)	0.402
3rd					1.02 (0.79, 1.30)	0.886
4th					1.08 (0.82, 1.43)	0.569
Most deprived					1.07 (0.79, 1.42)	0.660
Missing					0.99 (0.80, 1.22)	0.953

^aSample restricted to patients with at least 1 drug prescription. ^bIMD Index of Multiple Deprivation

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