Dynapenic obesity and the effect on long-term physical function and quality of life: data from the osteoarthritis initiative

Table 3 Multivariable regression analysis of primary outcome measures (n = 756)—males

	Gait speed			400 m walk			LLFDI-Frequency			LLFDI-Limitation			SF-12 PCS			SF-12 MCS
	β	SE	p	β	SE	p	β	SE	p	β	SE	p	β	SE	p	β	SE	p
Intercept	1.77	0.10	<0.001	411.5	12.33	<0.001	53.52	1.73	<0.001	109.4	4.61	<0.001	52.6	3.9	<0.001	54.1	3.49	<0.001
Age	−0.008	0.001	<0.001	−0.438	0.147	0.003	−0.103	0.021	<0.001	−0.481	0.056	<0.001	−0.162	0.05	0.001	0.031	0.041	0.46
Dynapenic obesity	−0.137	0.023	<0.001	−10.3	2.80	<0.001	1.55	0.419	<0.001	−5.00	1.12	<0.001	−6.12	0.89	<0.001	0.186	0.79	0.81
Dynapenia no obesity	−0.048	0.016	0.002	1.57	1.90	0.41	−0.63	0.26	0.15	−3.14	0.69	<0.001	−1.15	0.61	0.06	−0.101	0.54	0.85
Obesity no dynapenia	−0.087	0.016	<0.001	−0.97	1.90	0.61	−0.27	0.26	0.29	−4.44	0.69	<0.001	−2.40	0.61	<0.001	−0.931	0.54	0.09
Neither dynapenia nor obesity	Ref	Ref	Ref	Ref	Ref	Ref	Ref	Ref	Ref	Ref	Ref	Ref	Ref	Ref	Ref	Ref	Ref	Ref
Time	−0.01	0.002	<0.001	−0.141	0.430	0.74	--	--	--	--	--	--	−0.44	0.10	<0.001	−0.097	0.09	0.29
x Dyn obes	−0.0012	0.004	0.78	−8.07	1.07	<0.001	--	--	--	--	--	--	−0.05	0.24	0.84	0.033	0.22	0.88
X Dyn no obes	−0.008	0.003	0.79	−0.775	0.71	0.28	--	--	--	--	--	--	−0.35	0.16	0.03	0.165	0.15	0.27
x Obes no dyn	0.0026	0.003	0.37	−0.79	0.716	0.27	--	--	--	--	--	--	−0.06	0.16	0.70	−0.077	0.15	0.61
x No dyn no obes	Ref	Ref	Ref	Ref	Ref	Ref	--	--	--	--	--	--	Ref	Ref	Ref	Ref	Ref	Ref

All linear mixed models are adjusted for age, physical activity (Physical Activity Scale for the Elderly Score), smoking status, Charlson co-morbidity score, education, race, cohort type (incidence, progression, control). Referent category is the Neither dynapenia nor obesity group. Time-dependent co-variates are included in time x group interaction. LLDI was only available at 4-year follow-up thereby no time interaction term model was considered for this measure
Dyn dynapenia, Obes obesity, β beta-coefficient of regression model, SE standard errors, LLDI late-life functional and disability index, MCS mental component score, PCS physical component score, SF short form

ISSN: 1471-2318