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Table 1 Characteristics, functioning and anti-dementia drug use of patients by setting

From: Use of anti-dementia drugs in home care and residential care and associations with neuropsychiatric symptoms: a cross-sectional study

 

Total

Residential care

Home care

P- value

(n = 2821)

(n = 1439)

(n = 1382)

Characteristics

    

 Female, n (%)

1921 (68.1)

995 (69.1)

926 (67.0)

0.223

 Mean age, years (SD)

80.9 (10.1)

82.0 (9.8)

79.8 (10.4)

<0.001

   ≤ 64, n (%)

224 (8.0)

89 (6.2)

135 (10.6)

 

  65-74, n (%)

354 (12.6)

172 (11.0)

182 (12.5)

 

  75-84, n (%)

1056 (37.6)

511 (35.6)

545 (39.7)

 

   ≥ 85, n (%)

1174 (41.8)

664 (46.2)

513 (37.2)

 

Diagnosis and functioning

    

 Diagnosed dementia, n (%)

1184 (43.8)

774 (56.0)

410 (31.1)

<0.001

 ADL score (%, SD)

58.4 (34.3)

36.9 (30.8)

80.8 (20.9)

<0.001

  Bedridden, n (%)

233 (8.3)

221 (15.4)

12 (0.9)

<0.001

Drug use

    

 Total number of drugs, mean (SD)

8.6 (4.7)

8.5 (4.2)

8.5 (5.3)

0.437

 Anti-dementia drug users, n (%)

901 (31.9)

516 (35.9)

385 (27.9)

0.007

 AChEI alone, n (%)

545 (19.3)

262 (18.2)

283 (20.5)

0.015

  Donepezil, n (%)

291 (10.3)

127 (8.8)

161 (11.6)

 

  Rivastigmine, n (%)

153 (5.4)

99 (6.9)

54 (3.9)

 

  Galantamine, n (%)

107 (3.8)

36 (2.5)

69 (4.9)

 

 Memantine alone, n (%)

166 (5.8)

125 (8.7)

41 (3.0)

0.003

 AChEI and memantine

190 (6.7)

129 (9.0)

61 (4.4)

<0.001

  Donepezil + memantine, n (%)

94 (3.3)

60 (4.2)

34 (2.5)

 

  Rivastigmine + memantine, n (%)

63 (2.2)

51 (3.5)

12 (0.9)

 

  Galantamine + memantine, n (%)

33 (1.2)

18 (1.3)

15 (1.1)

 
  1. Chi-square test for categorical variables and Student’s t-test for continuous variables
  2. ADL score = Barthel Index, scale 0–100
  3. AChEI Acetylcholinesterase inhibitor