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Table 2 Univariate logistic regression model with CESD-R score status ( <16 vs. ≥ 16)a, N = 668*

From: Elevated circulating vascular cell Adhesion Molecule-1 (sVCAM-1) is associated with concurrent depressive symptoms and cerebral white matter Hyperintensities in older adults

Baseline Characteristics

OR

95%CI

P Value

Age, mean (SD), y

1.1

(0.99, 1.05)

0.30

Gender

   

Men

1.0

Reference

 

Women

1.4

(0.97, 2.01)

0.072

Race

   

Other race

1.0

Reference

 

White Race

0.8

(0.49, 1.28)

0.34

Body mass index, kg/m2,b

   

<25

1.18

(0.75, 1.66)

0.58

25-29.9

1.00

Reference

 

≥30

0.78

(0.50, 1.22)

0.27

Current smoker

0.96

(0.68, 1.36)

0.84

Alcohol use (Endorsing ≥2 drinks per week)

0.63

(0.42, 0.96)

0.031

Physical activity scorec

   

0- 66

1.81

(1.18, 2.77)

0.007

66.01-124

1.33

(0.86, 2.05)

0.20

124.01-559

1.00

Reference

 

Comorbidity index

1.49

(1.32, 167)

<.0001

Hypertension

1.50

(0.96, 2.36)

0.076

Hyperlipidemia

1.06

(0.74, 1.54)

0.74

Diabetes

1.48

(0.97, 2.25)

0.067

Previous Stroke

2.05

(1.21, 3.45)

0.0075

Cognitive impairment (MMSE < 24)d

2.14

(1.30, 3.55)

0.003

Congestive Heart failure

3.33

(1.66, 6.67)

0.0007

Coronary artery disease

1.23

(1.07, 1.43)

0.0048

Any cardiovascular medication

1.56

(1.06, 2.30)

0.025

Psychotropic Medication

1.50

(0.79, 2.81)

0.21

  1. *Missing values = 12 from 680.
  2. aCESD-R, Center for Epidemiological Studies Depression Scale Revised
  3. bBody mass index is calculated as weight in kilograms divided by height in meters squared
  4. cPhysical activity tertiles measured using the Physical Activity Scale for the Elderly
  5. dMini-Mental State Examination (MMSE) cut off point for cognitive impairment