Table 3 Multivariable logistic regression analysis for physical and mental decline

Lowest FEV₁/Ht³ quartile

1.54 (0.93-2.56)

1.45 (0.86-2.46)

1.70 (0.96-3.01)

1.89 (1.05-3.39)*

2.54 (1.49-4.32)**

2.36 (1.37-4.06)**

2.39 (1.32-4.33)**

2.39 (1.30-4.40)**

Age

1.11 (1.04-1.18)**

1.11 (1.04-1.19)**

1.10 (1.03-1.18)**

1.11 (1.04-1.19)**

1.10 (1.02-1.18)**

1.08 (1.00-1.17)*

Male

1.06 (0.66-1.70)

0.94 (0.49-1.79)

0.95 (0.49-1.90)

0.90 (0.53-1.54)

0.71 (0.34-1.48)

0.70 (0.32-1.50)

Smoker or ex-smoker

1.15 (0.60-2.20)

0.96 (0.49-1.90)

1.55 (0.75-3.21)

1.68 (0.79-3.56)

History of CVD

1.13 (0.70-1.83)

1.09 (0.67-1.80)

1.17 (0.68-2.00)

1.18 (0.68-2.06)

Hypertension

1.16 (0.69-1.96)

1.15 (0.66-1.98)

1.44 (0.80-2.62)

1.49 (0.80-2.78)

Diabetes

0.69 (0.37-1.29)

0.63 (0.33-1.19)

0.38 (0.17-0.84)*

0.40 (0.18-0.87)*

Parkinson disease

4.00 (0.56-28.46)

2.38 (0.27-21.45)

3.65 (0.47-28.42)

1.46 (0.10-20.41)

Osteoporosis

0.62 (0.33-1.16)

0.62 (0.33-1.17)

0.93 (0.48-1.82)

0.90 (0.45-1.79)

Asthma

2.41 (0.80-7.24)

2.63 (0.88-7.88)

1.01 (0.25-4.05)

1.09 (0.27-4.40)

COPD

0.44 (0.16-1.20)

0.47 (0.17-1.29)

0.52 (0.18-1.50)

0.50 (0.17-1.47)

Anemia

1.65 (0.89-3.04)

0.94 (0.46-1.91)

hs-CRP > 0.3 mg/dl

1.26 (0.76-2.08)

0.87 (0.49-1.54)

Serum creatinine >2 mg/dl

1.23 (0.37-4.08)

1.83 (0.53-6.32)