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Table 2 Combined association of chronic disease and low muscle mass with physical performance

From: Combined association of chronic disease and low skeletal muscle mass with physical performance in older adults in the Sarcopenia and Translational Aging Research in Taiwan (START) study

Chronic disease

Low ASMI

Total n

Low grip strength

Low gait speed

Low TUG test performance

n (%)

ORcrud(95%CI)

ORadj(95%CI)

n (%)

ORcrud(95%CI)

ORadj(95%CI)

n (%)

ORcrud(95%CI)

ORadj(95%CI)

Diabetes

           

No

No

1497

211 (14.09)

1.00

1.00

212 (14.16)

1.00

1.00

179 (11.96)

1.00

1.00

No

Yes

396

76 (19.19)

1.46 (1.09, 1.95)

1.52 (0.93, 2.48)

98 (24.75)

1.99 (1.52, 2.61)

2.03 (1.31, 3.12)

87 (21.97)

1.63 (1.22, 2.18)

1.65 (1.02, 2.68)

Yes

No

426

98 (23)

1.82 (1.39, 2.38)

1.36 (0.95, 1.96)

99 (23.24)

1.85 (1.42, 2.42)

1.76 (1.25, 2.47)

94 (22.07)

1.93 (1.45, 2.57)

1.90 (1.29, 2.79)

Yes

Yes

79

24 (30.38)

2.64 (1.60, 4.35)

2.43 (1.14, 5.17)

24 (30.38)

2.76 (1.67, 4.57)

2.73 (1.33, 5.59)

21 (26.58)

2.32 (1.36,3.97)

1.95 (0.87, 4.37)

Heart disease

          

No

No

1581

246 (15.56)

1.00

1.00

237 (14.99)

1.00

1.00

202 (12.78)

1.00

1.00

No

Yes

362

77 (21.27)

1.47 (1.11, 1.96)

1.56 (0.95, 2.56)

81 (22.38)

1.65 (1.24, 2.19)

1.73 (1.09, 2.73)

73 (20.17)

1.38 (1.03, 1.87)

1.38 (0.82, 2.35)

Yes

No

342

63 (18.42)

1.22 (0.90, 1.65)

1.19 (0.78, 1.83)

74 (21.64)

1.57 (1.17, 2.10)

1.23 (0.83, 1.80)

71 (20.76)

1.59 (1.17, 2.16)

1.43 (0.93, 2.21)

Yes

Yes

113

23 (20.35)

1.39 (0.86, 2.24)

1.94 (0.94, 3.99)

41 (36.28)

3.18 (2.12, 4.78)

2.97 (1.65, 5.34)

35 (30.97)

2.35 (1.53, 3.61)

2.48 (1.32, 4.65)

Hypertension

          

No

No

797

83 (10.41)

1.00

1.00

92 (11.54)

1.00

1.00

62 (7.78)

1.00

1.00

No

Yes

248

42 (16.94)

1.77 (1.19, 2.65)

1.93 (1.06, 3.52)

55 (22.18)

2.19 (1.51, 3.17)

2.20 (1.30, 3.72)

48 (19.35)

2.24 (1.48, 3.39)

2.31 (1.25, 4.25)

Yes

No

1126

226 (20.07)

2.16 (1.65, 2.83)

1.27 (0.90, 1.79)

219 (19.45)

1.86 (1.43, 2.42)

1.39 (1.00, 1.91)

211 (18.74)

2.53 (1.87, 3.44)

2.02 (1.37, 2.98)

Yes

Yes

227

58 (25.55)

2.95 (2.02, 4.29)

1.72 (0.97, 3.05)

67 (29.52)

3.23 (2.25, 4.62)

2.38 (1.43, 3.99)

60 (26.43)

3.26 (2.19, 4.85)

2.26 (1.27, 4.03)

Arthritis

           

No

No

1426

189 (13.25)

1.00

1.00

205 (14.38)

1.00

1.00

177 (12.41)

1.00

1.00

No

Yes

373

70 (18.77)

1.52 (1.12, 2.05)

1.72 (1.05, 2.81)

90 (24.13)

1.89 (1.43, 2.50)

1.88 (1.22, 2.90)

74 (19.84)

1.38 (1.02, 1.87)

1.28 (0.78, 2.10)

Yes

No

497

120 (24.14)

2.09 (1.62, 2.70)

1.30 (0.91, 1.86)

106 (21.33)

1.62 (1.25, 2.11)

1.47 (1.05, 2.06)

96 (19.32)

1.56 (1.18, 2.06)

1.18 (0.80, 1.75)

Yes

Yes

102

30 (29.41)

2.79 (1.77, 4.39)

1.60 (0.75, 3.40)

32 (31.37)

2.81 (1.80, 4.38)

3.06 (1.52, 6.15)

34 (33.33)

2.87 (1.83, 4.50)

2.93 (1.41, 6.10)

Osteoporosis

          

No

No

1574

245 (15.57)

1.00

1.00

227 (14.42)

1.00

1.00

203 (12.9)

1.00

1.00

No

Yes

382

80 (20.94)

1.44 (1.09, 1.91)

1.65 (1.02, 2.68)

94 (24.61)

1.94 (1.48, 2.55)

1.90 (1.23, 2.93)

80 (20.94)

1.44 (1.07, 1.92)

1.44 (0.88, 2.35)

Yes

No

349

64 (18.34)

1.22 (0.90, 1.66)

1.03 (0.70, 1.51)

84 (24.07)

1.89 (1.42, 2.51)

1.39 (0.97, 1.99)

70 (20.06)

1.59 (1.17, 2.17)

1.31 (0.86, 1.98)

Yes

Yes

93

20 (21.51)

1.52 (0.91, 2.54)

1.35 (0.62, 2.98)

28 (30.11)

2.56 (1.61, 4.08)

2.78 (1.41, 5.48)

28 (30.11)

2.32 (1.44, 3.73)

2.25 (1.07, 4.71)

  1. ASMI = Appendicular Skeletal Muscle Mass Index; BMI = body mass index; CI = confidence interval; OR = odds ratio; ORadj = OR adjusted for age, sex, education, BMI, site, tobacco, alcohol, marital status, physical activity, and other chronic diseases.