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Table 3 Association between Inappropriate Medication Use and Risk of Fall

From: Inappropriate medication use and risk of falls – A prospective study in a large community-dwelling elderly cohort

  ≤ 1 fall ≥ 2 falls     
Medication n (%) (N = 4961) (N = 1382) RR (95% CI) crude P-value RR (95% CI)* P-value*
Inappropriate medication, full list 1500 (30.2) 504 (36.5)     
Inappropriate medication, excluding cerebral vasodilators 924 (18.6) 315 (22.8) 1.27 (1.12–1.43) <.001 1.05 (0.92–1.20) .47
Long-acting benzodiazepines 351 (7.1) 144 (10.4) 1.46 (1.23–1.74) <.001 1.20 (1.00–1.43) .048
Inappropriate psychotropic drugs 108 (2.2) 47 (3.4) 1.60 (1.20–2.14) .002 1.31 (0.97–1.76) .08
Inappropriate medication with anticholinergic properties 223 (4.5) 92 (6.7) 1.50 (1.21–1.85) <.001 1.18 (0.96–1.47) .13
Short- or intermediate-half-life benzodiazepines 568 (11.5) 206 (14.9) 1.31 (1.13–1.51) <.001 0.99 (0.85–1.16) .89
  1. * Adjusted for age, sex, study centre, body mass index, diurnal drowsiness, number of drugs (excluding inappropriate medication), cognitive functioning, depressive symptoms and impaired mobility.
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