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Table 4 Age-related IGF-1 plasma concentrations.

From: A polymorphic variant of the insulin-like growth factor 1 (IGF-1) receptor correlates with male longevity in the Italian population: a genetic study and evaluation of circulating IGF-1 from the "Treviso Longeva (TRELONG)" study

Age bracket No. of people IGF-1 [ng/mL] (mean ± SD)
5 years   
70 – 75 103 192 ± 80
76 – 80 119 197 ± 89
81 – 85 96 184 ± 77
86 – 90 73 159 ± 68**
91 – 95 138 171 ± 76
96 – 100 29 146 ± 51**
100+ 6 117 ± 87
10 years   
70 – 79 195 199 ± 88
80 – 89 177 174 ± 70 #
90 – 99 186 168 ± 75 #
>99 6 132 ± 63
  1. ** p < 0.01 vs. (70–75) group and #p <0.01 vs. (70–79) group, one-way ANOVA followed by Dunnett's post-hoc test; SD: standard deviation, M: men; F: women.