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Table 2 rs2229765 genotypic and allelic frequencies according to age and sex.

From: A polymorphic variant of the insulin-like growth factor 1 (IGF-1) receptor correlates with male longevity in the Italian population: a genetic study and evaluation of circulating IGF-1 from the "Treviso Longeva (TRELONG)" study

  Genotype count (%) Allele count (%)   
Age bracket (no. of people) G/G G/A A/A G A χ2 p-value (genotypic distribution) χ2 p-value (allelic distribution)
70–85 (288) 102 (35.4) 147 (51.1) 39 (13.5) 351 (61.0) 225 (39.0)   
M (147) 59(40.0) 75 (51.0) 13 (9.0) 193 (65.6) 101 (34.4)   
F (141) 43 (30.5) 72 (51.0) 26 (18.5)a 158 (56.0) 124 (44.0)b ap = 0.03 b p = 0.02
85+ (222) 70 (31.5) 110 (49.5) 42 (19.0) 250 (56.3) 194 (43.7)   
M (89) 26 (29.2) 48 (53.9) 15 (16.8) 100 (56.2) 78 (43.7)c   c p = 0.04
F (133) 44 (33.1) 62 (46.6) 27 (20.4)d 150 (56.4) 116 (43.6)e d p = 0.02 e p = 0.02
  1. a: χ2 p-value for the comparison of the genotype count distribution between males 70–85 and females 70–85; b: χ2 p-value for the comparison of the allele count distribution between males 70–85 and females 70–85; c: χ2 p-value for the comparison of the allele count distribution between males 70–85 and males 85+; d: χ2 p-value for the comparison of the genotype count distribution between males 70–85 and females 85+; e: χ2 p-value for the comparison of the allele count distribution between males 70–85 and females 85+.
  2. M: men, F: women.