The association of APOE genotype and cognitive decline in interaction with risk factors in a 65–69 year old community sample

Table 3 Multivariate models of change scores

	SDMT		Immediate recall		Delayed recall		Digits Backwards		MMSE		Simple RT		Choice RT
	F	p	F	p	F	p	F	p	F	p	F	p	F	p
APOE Genotype	3.20	0.041	0.92	0.397	1.70	0.182	3.14	0.044	2.58	0.076	0.16	0.853	0.30	0.743
Education	2.09	0.099	0.86	0.461	0.32	0.812	1.61	0.185	2.49	0.059	0.08	0.971	0.51	0.674
Head injury	0.00	0.962	0.67	0.415	1.17	0.280	1.18	0.277	4.91	0.027	0.00	0.992	0.46	0.495
Premorbid intelligence	0.05	0.955	0.05	0.950	1.56	0.209	1.02	0.360	0.64	0.525	0.06	0.944	0.18	0.838
Genotype × Education	0.98	0.438	2.23	0.038	2.88	0.008	1.65	0.130	1.17	0.322	1.19	0.310	1.11	0.357
Genotype × Head injury	3.94	0.020	0.22	0.801	1.17	0.312	0.70	0.499	3.82	0.022	0.03	0.975	0.27	0.765
Genotype × Premorbid intelligence	0.47	0.757	1.04	0.388	2.32	0.054	1.07	0.370	2.71	0.029	2.04	0.087	0.35	0.842
Education × Head injury	1.72	0.160	1.04	0.375	0.12	0.951	1.26	0.285	2.68	0.045	0.55	0.650	0.78	0.504
Education × Premorbid intelligence	1.83	0.089	0.75	0.607	0.58	0.750	0.56	0.761	2.26	0.035	1.13	0.342	0.58	0.745
Head injury × Premorbid intelligence	0.25	0.778	1.18	0.307	0.06	0.941	0.97	0.379	0.13	0.879	0.83	0.435	1.38	0.253

ISSN: 1471-2318