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Table 3 30-day mortality and mortality rate ratios (MRR) for patients with perforated and bleeding peptic ulcer stratified by level of comorbidity.

From: Short-term mortality after perforated or bleeding peptic ulcer among elderly patients: a population-based cohort study

Comorbidity score Ω

Age (years)

Number of patients

30-day mortality

Crude 30-day MRR (95% CI)

Adjusted 30-day MRR* (95% CI)

Perforated Peptic ulcer

Low

15–64

616

6.0%

1 (ref)

1 (ref)

 

65–79

378

20.9%

3.8 (2.5–5.6)

3.5 (2.3–5.1)

 

80+

273

41.0%

8.6 (5.9–12.4)

8.1 (5.5–11.9)

Moderate

15–64

161

16.8%

1 (ref)

1 (ref)

 

65–79

290

34.8%

2.3 (1.5–3.4)

2.1 (1.4–3.2)

 

80+

208

50.0%

3.8 (2.5–5.7)

3.4 (2.3–5.3)

High

15–64

28

28.6%

1 (ref)

1 (ref)

 

65–79

75

42.7%

1.6 (0.8–3.6)

1.6 (0.7–3.6)

 

80+

32

62.5%

3.0 (1.3–6.7)

2.9 (1.2–6.8)

Bleeding Peptic ulcer

Low

15–64

1422

3.4%

1 (ref)

1 (ref)

 

65–79

1322

6.7%

2.0 (1.4–2.9)

1.9 (1.3–2.7)

 

80+

1148

16.0%

4.9 (3.6–6.8)

4.5 (3.3–6.2)

Moderate

15–64

523

5.5%

1 (ref)

1 (ref)

 

65–79

1139

13.4%

2.5 (1.7–3.7)

2.5 (1.7–3.7)

 

80+

1012

16.9%

3.2 (2.2–4.8)

3.2 (2.2–4.8)

High

15–64

141

9.2%

1 (ref)

1 (ref)

 

65–79

313

13.7%

1.5 (0.8–2.8)

1.5 (0.8–2.7)

 

80+

212

25.0%

2.9 (1.6–5.1)

2.7 (1.5–4.9)

  1. Ω Three levels of the index were defined: Low (no co-morbidity), medium (Charlson Index 1–2) and high (Charlson Index 3+). * Adjusted in a Cox regression model for gender, previous admissions with uncomplicated peptic ulcer and ulcer-related drug use.