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Table 4 Prevalence of inappropriate drug prescription (Dependent on disease or condition)

From: Prevalence of inappropriate medication using Beers criteria in Japanese long-term care facilities

Disease or condition

Drug

Severity

n/N *

%

Heart failure

Disopyramide, high sodium content drugs

High

4/114

3.5

Seizures or epilepsy

Chlorpromazine, thioridazine

High

2/57

3.5

Blood clotting disorders or receiving anticoagulant therapy

Aspirin, NSAIDs, dipyridamole, ticlopidine

High

4/27

14.8

Stress incontinence**

α-Blockers, anticholinergics, tricyclic antidepressants, long-acting benzodiazepines

High

89/1028

8.7

Arrhythmias

Tricyclic antidepressants

High

1/106

0.9

Insomnia

Decongestants, theophylline, methylphenidate, MAOI, amphetamines

High

4/92

4.3

Parkinson's disease

Metoclopramide, conventional antipsychotics

High

19/88

11.4

Cognitive impairment

Barbiturates, anticholinergics, antispasmodics, muscle relaxants, CNS stimulants

High

52/1273

4.1

Depression

Sympatholytic agents

High

8/119

6.7

Syncope or falls

Short to intermediate-acting benzodiazepine, tricyclic antidepressants

High

23/103

22.3

COPD

Long-acting benzodiazepines, β-blockers

High

1/44

2.3

Chronic constipation

Calcium channel blockers, anticholinergics, tricyclic antidepressants

Low

165/548

30.1

Use of any of above for each disease or condition

300/1669

18.0

  1. * N: Number of patients with the disease or condition. n: Number of patients treated with any of drug(s) that are inappropriate for that disease or condition.
  2. ** We could not identify the patients with 'stress incontinence' because the MDS data were limited to 'incontinence' in general.