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Table 2 Patient characteristics-antihistamines

From: Association of skeletal muscle relaxers and antihistamines on mortality, hospitalizations, and emergency department visits in elderly patients: a nationwide retrospective cohort study

Variable N(%) Unmatched Characteristics Matched Demographic Characteristics (1:1 propensity-scored matching)
Variable N(%) Incident Antihistamine Use No Antihistamine Use P value Incident Antihistamine Use No Antihistamine Use P value
n = 30031 n = 1777373 n = 30029 n = 30029
Age Groups       
  65-74 14853 (49.5%) 805052 (45.3%) <0.001 14851 (49.5%) 14848 (49.5%) 0.993
  75-84 12728 (42.4%) 815731 (45.9%) 12728 (42.4%) 12738 (42.4%)
  85+ 2450 (8.2%) 156590 (8.8%) 2450 (8.1%) 2443 (8.1%)
Gender (female) 740 (2.5%) 28386 (1.6%) <0.001 738 (2.5%) 722 (2.4%) 0.672
Race/Ethnicity       
  White 21392 (71.2%) 1171262 (65.9%) <0.001 21392 (71.2%) 21408 (71.3%) 0.995
  Black 3197 (10.7%) 109686 (6.2%) 3195 (10.6%) 3196 (10.6%)
  Hispanic 1677 (5.6%) 54610 (3.1%) 1677 (5.6%) 1655 (5.5%)
  Other 482 (1.6%) 22347 (1.3%) 482 (1.6%) 476 (1.6%)
  Unknown/missing 3283 (10.9%) 419468 (23.6%) 3283 (10.9%) 3294 (11%)
Poverty Status       
  Under the poverty limit 23780 (79.2%) 1035894 (58.3%) <0.001 23778 (79.2%) 23790 (79.2%) 0.602
Number of Medications       
  0-5 7451 (24.8%) 871449 (49%) <0.001 7451 (24.8%) 7447(24.8%) 1.000
  6-8 7045 (23.5%) 458910 (25.8%) 7045 (23.5%) 7049 (23.5%)  
  9-11 6292 (21%) 248537 (14%) 6292 (21%) 6301 (21%)
  >12 9243 (30.8%) 198477 (11.2%) 9241 (30.8%) 9232 (30.7%)
Number of Physical Comorbidities       
  0-1 5174 (17.2%) 844104 (47.5%) <0.001 5174 (17.2%) 5160 (17.2%) 0.997
  2-3 12485 (41.6%) 328371 (18.5%) 12485 (41.6%) 12497 (41.6%)
  4-5 8114 (27%) 96228 (5.4%) 8113 (27%) 8127 (27.1%)
  6+ 4258 (14.2%) 508670 (28.6% 4257 (14.2%) 4245 (14.1%)
Number of Psychiatric Comorbidities       
  0 23260 (77.5%) 1554672 (87.5%) <0.001 23260 (77.5%) 23263 (77.5%) 0.958
  1 4906 (16.3%) 178882 (10.1%) 4906 (16.3%) 4919 (16.4%)
  2+ 1865 (6.2%) 43819 (2.4%) 1863 (6.2%) 1847 (6.2%)
ED visits in 2005 10345 (34.5%) 241958 (13.6%) <0.001 10343 (34.4%) 10343 (34.4%) 1.000
Hospital admissions in 2005 4472 (14.9%) 94854 (5.3%) <0.001 4471 (14.9%) 4456 (14.8%) 0.863
Geriatric visits in 2005 867 (2.9%) 42236 (2.4%) <0.001 867 (2.9%) 847 (2.8%) 0.624
Primary Care visits       
  0-1 3975 (13.2%) 478627 (26.9%) <0.001 3975 (13.2%) 3969 (13.2%) 0.997
  2-4 15017 (50%) 991222 (55.8%) 15016 (50%) 15018 (50%)
  5+ 11039 (36.8%) 307524 (17.3%) 11038 (36.8%) 11042 (36.8%)
Outcomes       
Death within 1 year 3685 (12.2%) 77318 (4.4%) <0.001 3684 (12.3%) 2033 (6.8%) <0.001
Emergency department visit within 1 year 13267 (44.2%) 230839 (13%) <0.001 13266 (44.2%) 7562 (25.2%) <0.001
Hospitalization within 1 year 5729 (19.1%) 81389 (4.6%) <0.001 5729 (19.1%) 2895 (9.6%) <0.001
Emergency department visit for fall within 1 year 383 (1.3%) 6488 (0.4%) <0.001 383 (1.3%) 216 (0.7%) <0.001
Hospitalization for fall within 1 year 109 (0.4%) 1583 (0.1%) <0.001 109 (0.4%) 56 (0.2%) <0.001
Death emergency department visit or hospitalization within 1 year (composite) 16142 (53.8%) 304362 (17.1%) <0.001 16141 (53.8%) 9276 (30.9%) <0.001