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Table 1 Patient characteristics-skeletal muscle relaxant

From: Association of skeletal muscle relaxers and antihistamines on mortality, hospitalizations, and emergency department visits in elderly patients: a nationwide retrospective cohort study

Variable N(%)

Unmatched characteristics

Matched Demographic Characteristics (1:1 propensity-scored matching)

 

Incident Muscle Relaxant Use

No Muscle Relaxant Use

P value

Incident Muscle Relaxant Use

No Muscle Relaxant Use

P value

n = 27786

n = 1779618

 

n = 27783

n = 27783

Age Groups

      

  65-74

16216 (58.4%)

803689 (45.2%)

<0.001

16213 (58.4%)

16205 (58.3%)

0.994

  75-84

10207 (36.7%)

818252 (46%)

 

10207 (36.7%)

10210 (36.8%)

  85+

1363 (4.9%)

157677 (8.9%)

 

1363 (4.9%)

1368 (4.9%)

Gender (female)

668 (2.4%)

28458 (1.6%)

<0.001

665 (2.4%)

637 (2.3%)

0.432

Race/Ethnicity

      

  White

19072 (68.6%)

1173582 (66%)

<0.001

19072 (68.7%)

19083 (68.7%)

1.00

  Black

2841 (10.2%)

110042 (6.2%)

 

2839 (10.2%)

2838 (10.2%)

  Hispanic

1854 (6.7%)

54433 (3.1%)

 

1853 (6.7%)

1854 (6.7%)

  Other

393 (1.4%)

22436 (1.3%)

 

393 (1.4%)

391 (1.4%)

  Unknown/missing

3626 (13.1%)

419125 (23.6%)

 

3626 (13.1%)

3617 (13%)

Poverty Status

      

Under the poverty limit

20873 (75.1%)

1038801 (58.4%)

<0.001

20870 (75.1%)

20886 (75.2%)

0.895

Number of Medications

      

  0-5

7900 (28.4%)

871000 (48.9%)

<0.001

7900 (28.4)

7900 (28.4)

1.00

  6-8

6811 (24.5%)

459144 (25.8%)

 

6810 (24.5%)

6808 (24.5%)

  9-11

5601 (20.2%)

249228 (14%)

 

5601 (20.2%)

5595 (20.1%)

  >12

7474 (26.9%)

200246 (11.3%)

 

7472 (26.9%)

7480 (26.9%)

Number of Physical Comorbidities

      

  0-1

5107 (18.4%)

508737 (28.6%)

<0.001

5107 (18.4%)

5123 (18.4%)

0.996

  2-3

12041 (43.3%)

844548 (47.5%)

 

12040 (43.3%)

12040 (43.3%)

  4-5

7387 (26.6%)

329098 (18.5%)

 

7385 (26.6%)

7385 (26.6%)

  6+

3251 (11.7%)

97235 (5.5%)

 

3251 (11.7%)

3235 (11.7%)

Number of Psychiatric Comorbidities

      

  0

22267 (80.1%)

1555665 (87.4%)

<0.001

22267 (80.1%)

22263 (80.1%)

0.993

  1

4093 (14.7%)

179695 (10.1%)

 

4091 (14.7%)

4099 (14.7%)

  2+

1426 (5.1%)

44258 (2.5%)

 

1425 (5.1%)

1421 (5.1%)

ED visits in 2005

8439 (30.4%)

243864 (13.7%)

<0.001

8436 (30.4%)

8441 (30.4%)

0.963

Hospital admissions in 2005

3050 (11%)

96276 (5.4%)

<0.001

3049 (11%)

3046 (11%)

0.968

Geriatric visits in 2005

553 (2%)

42550 (2.4%)

<0.001

553 (2%)

551 (2%)

0.952

Primary Care visits

      

  0-1

3639 (13.1%)

478963 (26.9%)

<0.001

3639 (13.1%)

3639 (13.1%)

0.993

  2-4

14736 (53%)

991503 (55.7%)

 

14736 (53%)

14749 (53.1%)

  5+

9411 (33.9%)

309152 (17.4%)

 

9411 (33.9%)

9398 (33.8%)

Outcomes

      

Death within 1 year

1414 (5.1%)

79589 (4.5%)

<0.001

1414 (5.1%)

1613 (5.8%)

<0.001

Emergency department visit within 1 year

11169 (40.2%)

232937 (13.1%)

<0.001

11169 (40.2%)

6399 (23.0%)

<0.001

Hospitalization within 1 year

3613 (13%)

83505 (4.7%)

<0.001

3613 (13%)

2430 (8.8%)

<0.001

Emergency department visit for fall within 1 year

384 (1.4%)

6487 (0.4%)

<0.001

384 (1.4%)

176 (0.63%)

<0.001

Hospitalization for fall within 1 year

67 (0.2%)

1625 (0.1%)

<0.001

67 (0.24%)

46 (0.17%)

0.048

Death emergency department visit or hospitalization within 1 year (composite)

12365 (44.5%)

308148 (17.3%)

<0.001

12356 (44.5%)

7821 (28.2%)

<0.001