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Table 4 Survival models for study-defined delirium

From: The descriptive epidemiology of delirium symptoms in a large population-based cohort study: results from the Medical Research Council Cognitive Function and Ageing Study (MRC CFAS)

Ā 

N

Missing data

HR

LCI

UCI

P

Delirium symptom clusters

Ā Ā Ā Ā Ā Ā 

Inattention

2637

3

1.36

1.16

1.58

<0.01

Acute change

2184

13

1.57

1.33

1.85

<0.01

Fluctuation

2184

13

1.40

1.21

1.62

<0.01

Drowsiness

2184

13

1.31

1.08

1.57

<0.01

Judged delirium*

2184

13

1.92

1.35

2.74

<0.01

Delirium: final model

2159

38

Ā Ā Ā Ā 

ā€ƒDelirium

Ā Ā 

1.28

1.03

1.60

0.03

ā€ƒDementia

Ā Ā 

1.83

1.63

2.06

<0.01

ā€ƒAge (per year)

Ā Ā 

1.08

1.08

1.09

<0.01

ā€ƒSex (women versus men)

Ā Ā 

0.68

0.61

0.75

<0.01

ā€ƒIllness severity

Ā Ā Ā Ā Ā Ā 

ā€ƒā€ƒNone

Ā Ā 

[Ref]

Ā Ā Ā 

ā€ƒā€ƒMild

Ā Ā 

1.47

1.15

1.88

<0.01

ā€ƒā€ƒModerate

Ā Ā 

1.52

1.10

2.12

<0.01

ā€ƒā€ƒSevere

Ā Ā 

3.14

2.23

4.42

<0.01

Subsyndromal delirium: final model

2159

38

Ā Ā Ā Ā 

ā€ƒSybsyndromal delirium

Ā Ā 

1.41

1.23

1.62

<0.01

ā€ƒDementia

Ā Ā 

1.62

1.42

1.85

<0.01

ā€ƒAge (per year)

Ā Ā 

1.08

1.07

1.09

<0.01

ā€ƒSex (women versus men)

Ā Ā 

0.67

0.61

0.75

<0.01

ā€ƒIllness severity

Ā Ā Ā Ā Ā Ā 

ā€ƒā€ƒNone

Ā Ā 

[Ref]

Ā Ā Ā 

ā€ƒā€ƒMild

Ā Ā 

1.32

1.03

1.70

0.03

ā€ƒā€ƒModerate

Ā Ā 

1.50

1.10

2.06

0.01

ā€ƒā€ƒSevere

Ā Ā 

2.94

2.10

4.12

<0.01

  1. HR hazard ratio, LCI UCI 95% lower and upper confidence intervals respectively.
  2. This table shows Cox proportional hazard models for death.
  3. ā€œDelirium symptom clustersā€ shows individual symptom clusters, and their association with mortality (adjusted for age, sex, baseline dementia and illness severity), i.e. the independent effects of each symptom cluster.
  4. *ā€˜Judged deliriumā€™ refers to the overall impression of the interviewer that a participant had delirium.
  5. ā€œDelirium: final modelā€ refers to the full model for full syndromal delirium and the same adjusted covariates.
  6. ā€œSubsyndromal delirium: final modelā€ describes the full model for subsyndromal delirium and the same adjusted covariates.
  7. Missing data. These arise through non-responses in interviewed participants or respondents. Estimated models are based on complete cases, i.e. where all covariates are complete for the sample.