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Table 4 Predictors of UTI antibiotic resistance in Escherichia coli 1 in voided urine specimens

From: Antimicrobial resistance in urinary pathogens among Swedish nursing home residents remains low: a cross-sectional study comparing antimicrobial resistance from 2003 to 2012

 

Unadjusted odds ratios (95% CI; p-value)

Adjusted odds ratios (95% CI; p-value)

Mecillinam

  

  Antibiotics last month2

7.2 (2.4-21; p = 0.00040)

7.1 (2.4-21; p = 0.00049)

  Age

1.0 (0.94-1.1; p = 0.65)

1.0 (0.94-1.1; p = 0.62)

  Gender3

<10-6 (0-∞; p = 1.0)

<10-6 (0-∞; p = 1.0)

Ampicillin

  

  Antibiotics last month2

5.2 (2.4-11; p = 0.000030)

5.2 (2.4-11; p = 0.000036)

  Age

1.0 (0.98-1.1; p = 0.40)

1.0 (0.97-1.1; p = 0.42)

  Gender3

0.26 (0.033-2.0; p = 0.20)

0.32 (0.040-2.6; p = 0.28)

Cefadroxil

  

  Antibiotics last month2

<10-6 (0-∞; p = 1.0)

<10-6 (0-∞; p = 1.0)

  Age

1.1 (0.91-1.4; p = 0.28)

1.1 (0.91-1.4; p = 0.30)

  Gender3

<10-6 (0-∞; p = 1.0)

<10-6 (0-∞; p = 1.0)

Trimethoprim

  

  Antibiotics last month2

4.0 (1.7-9.4; p = 0.0018)

3.9 (1.6-9.2; p = 0.0023)

  Age

1.0 (0.96-1.1; p = 0.60)

1.0 (0.96-1.1; p = 0.65)

  Gender3

<10-6 (0-∞; p = 1.0)

<10-6 (0-∞; p = 1.0)

Nitrofurantoin

  

  Antibiotics last month2

1.0×108 (0-∞; p = 1.0)

1.1×108 (0-∞; p = 0.99)

  Age

1.2 (0.90-1.6; p = 0.22)

1.3 (0.88-1.8; p = 0.21)

  Gender3

<10-6 (0-∞; p = 1.0)

1.2×10-5 (0-∞; p = 1.0)

Nalidixic acid 4 2003

  

  Antibiotics last month2

4.3 (1.4-13; p = 0.013)

4.6 (1.4-16; p = 0.014)

  Age

0.92 (0.87-0.98; p = 0.014)

0.92 (0.86-0.99; p = 0.018)

  Gender3

<10-6 (0-∞; p = 1.0)

<10-6 (0-∞; p = 1.0)

Ciprofloxacin 5 2012

  

  Antibiotics last month2

3.1 (0.30-32; p = 0.35)

3.6 (0.32-40; p = 0.31)

  Age

1.1 (0.91-1.3; p = 0.38)

1.1 (0.90-1.3; p = 0.36)

  Gender3

<10-6 (0-∞; p = 1.0)

<10-6 (0-∞; p = 1.0)

  1. 1N = 255 (22 sparse growth and 233 significant growth), voided urine specimens in 2003 and 2012 from patients with known antibiotic treatment history.
  2. 2Any ongoing (n = 8) or previous antibiotic treatment during the last month (n = 25). Reference category: no antibiotics last month.
  3. 3Reference category: female.
  4. 4Only includes residents from 2003 since nalidixic acid only was tested in 2003 (n = 138).
  5. 5Only includes residents from 2012 since ciprofloxacin only was tested in 2012 (n = 117).
  6. Statistically significant findings are bold.