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Table 5 Application of UK-NOS triage approach combining phalangeal RA and calcaneal QUS

From: Calcaneal quantitative ultrasound and Phalangeal radiographic absorptiometry alone or in combination in a triage approach for assessment of osteoporosis: a study of older women with a high prevalence of falls

Combined test phalangeal RA and Calcaneal QUS (n = 202) UK-NOS triage approach 85% certainty level 95% CI UK-NOS triage approach 90% certainty level 95% CI UK-NOS triage approach 95% certainty level 95% CI
RA T-score, upper/lower cutoff -1.36/–2.52 NA -0.65/–2.75 NA 0.28/–3.32 NA
QUS BUA, upper/lower cutoff 101.74/89.63 NA 105.88/86.63 NA 114.5/80.09  
Sensitivity (%) 98.9 94.1–100 100 96.1–100 100 96.1–100
Specificity (%) 95.5 89.7–98.5 99.1 95.0–100 100 96.7–100
PPV (%) 87.2 72.6–95.7 94.7 74.0–99.9 100 54.1–100
NPV (%) 97.5 86.8–99.9 100 86.3–100 100 75.3–100
False negative (%) 0.5 0.01–2.7 0 0–0.2 0 0–3.2
False positive (%) 2.5 0.8–5.7 0.5 0.01–2.7 0 0–3.9
DXA scans avoided (%) 41.1 34.2-48.2 21.8 16.3–28.1 9.4 6.2–14.9
  1. Application of UK-NOS triage approach combining phalangeal RA and calcaneal QUS at a certainty level of 85%, 90%, or 95% for each method. Abbreviations: QUS Quantitative Ultrasound, BUA Broadband Ultrasound Attenuation, RA Radiographic Absorptiometry, UK-NOS United Kingdom National Osteoporosis Society, PPV Positive Predictive Value, NPV Negative Predictive Value, DXA Dual Energy X-ray Absorptiometry, CI Confidence Interval, NA not available.