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Table 3 Univariate predictors of occurrence of falls during follow-up

From: Fall predictors in older cancer patients: a multicenter prospective study

Variable

 

Total population

(n = 809)*

Non-fallers

(no falls)

(n = 667)*

Fallers

(≥1 fall)

(n = 142)*

Single fallers

(1 fall)

(n = 69)*

Recurrent fallers

(≥2 falls)

(n = 73)*

P-value non-fallers vs fallers

P-value non-fallers vs single fallers

P-value non-fallers vs recurrent fallers

Age

70-74

322 (39.8%)

278 (41.7%)

44 (31.0%)

23 (33.3%)

21 (28.8%)

0.0511

0.0955

0.1703

75-79

256 (31.6%)

207 (31.0%)

49 (34.5%)

20 (29.0%)

29 (39.7%)

≥80

231 (28.6%)

182 (27.3%)

49 (34.5%)

26 (37.7%)

23 (31.5%)

Gender

Female

528 (65.3%)

435 (65.2%)

93 (65.5%)

45 (65.2%)

48 (65.8%)

0.95

1.0

0.93

Male

281 (34.7%)

232 (34.8%)

49 (34.5%)

24 (34.8%)

25 (34.3%)

G8

No geriatric risk profile (>14)

232 (28.7%)

218 (32.7%)

14 (9.9%)

6 (8.7%)

8 (11.0%)

<0.0001

<0.0001

0.0001

Geriatric risk profile (≤14)

577 (71.3%)

449 (67.3%)

128 (90.1%)

63 (91.3%)

65 (89.0%)

fTRST

No geriatric risk profile (0)

153 (18.9%)

147 (22.0%)

6 (4.2%)

2 (2.9%)

4 (5.5%)

<0.0001

0.0002

0.0009

Geriatric risk profile (≥1)

656 (81.1%)

520 (78.0%)

136 (95.8%)

67 (97.1%)

69 (94.5%)

ADL

Independent (6)

413 (51.1%)

375 (56.2%)

38 (26.8%)

16 (23.2%)

22 (30.1%)

<0.0001

<0.0001

<0.0001

Dependent (≥7)

396 (48.9%)

292 (43.8%)

104 (73.2%)

53 (76.8%)

51 (69.9%)

IADL

Independent (5(male)/8(female)

367 (45.4%)

325 (48.7%)

42 (29.6%)

18 (26.1%)

24 (32.9%)

<0.0001

0.0003

0.01

Dependent (≤4(male)/≤7(female))

442 (54.6%)

342 (51.3%)

100 (70.4%)

51 (73.9%)

49 (67.1%)

Living situation

Not living alone

571 (70.6%)

486 (72.9%)

85 (59.9%)

42 (60.9%)

43 (58.9%)

0.002

0.0352

0.01

Living alone

238 (29.4%)

181 (27.1%)

57 (40.1%)

27 (39.1%)

30 (41.1%)

Fall history in the past 12 months

No falls

566 (70.0%)

510 (76.5%)

56 (39.4%)

32 (46.4%)

24 (32.9%)

<0.0001

<0.0001

<0.0001

Falls (≥1)

243 (30.0%)

157 (23.5%)

86 (60.6%)

37 (53.6%)

49 (67.1%)

CCI

No comorbidities (0)

388 (48.0%)

326 (48.9%)

62 (43.7%)

27 (39.1%)

35 (47.9%)

0.26

0.1230

0.88

Comorbidities (≥1)

421 (52.0%)

341 (51.1%)

80 (56.3%)

42 (60.9%)

38 (52.1%)

MOB-T for fatigue

No fatigue

339 (41.9%)

313 (46.9%)

26 (18.3%)

12 (17.4%)

14 (19.2%)

<0.0001

<0.0001

<0.0001

Fatigue

470 (58.1%)

354 (53.1%)

116 (81.7%)

57 (82.6%)

59 (80.8%)

Poly-pharmacy

Absence (0–4 drugs)

386/785 (49.2%)

338/649 (52.1%)

48/136 (35.3%)

22/66 (33.3%)

26/70 (37.1%)

0.0004

0.0037

0.02

Presence (≥5 drugs)

399/785 (50.8%)

311/649 (47.9%)

88/136 (64.7%)

44/66 (66.7%)

44/70 (62.9%)

VAS for pain

No pain (0)

408 (50.4%)

359 (53.8%)

49 (34.5%)

23 (33.3%)

26 (35.6%)

<0.0001

0.0012

0.003

Mild pain/pain to treat (1–10)

401 (49.6%)

308 (46.2%)

93 (65.5%)

46 (66.7%)

47 (64.4%)

MMSE

Normal cognition (≥24)

738 (91.2%)

615 (92.2%)

123 (86.6%)

59 (85.5%)

64 (87.7%)

0.03

0.0566

0.18

Mild/severe cognitive decline (≤23)

71 (8.8%)

52 (7.8%)

19 (13.4%)

10 (14.5%)

9 (12.3%)

GDS

Not at risk for depression (0–4)

663/806 (82.3%)

559/665 (84.1%)

104/141 (73.8%)

52/68 (76.5%)

52 (71.2%)

0.004

0.1095

0.006

At risk for depression (≥5)

143/806 (17.7%)

106/665 (15.9%)

37/141 (26.2%)

16/68 (23.5%)

21 (28.8%)

MNA-SF

Normal nutritional status (≥12)

412 (50.9%)

367 (55.0%)

45 (31.7%)

21 (30.4%)

24 (32.9%)

<0.0001

<0.0001

0.0003

Risk of malnutrition/malnourished (≤11)

397 (49.1%)

300 (45.0%)

97 (68.3%)

48 (69.6%)

49 (67.1%)

ECOG PS

Score 0-1

619/808 (76.6%)

529/666 (79.4%)

90 (63.4%)

42 (60.9%)

48 (65.8%)

<0.0001

0.0004

0.0073

 

Score 2-4

189/808 (23.4%)

137/666 (20.6%)

52 (36.6%)

27 (39.1%)

25 (34.3%)

   
  1. Legend: fTRST: Flemish version of Triage Risk Screening Tool; ADL : Activities of Daily Living; IADL : Instrumental Activities of Daily Living; CCI: Charlson Comorbidity Index; MOB-T : Mobility-Tiredness test; VAS: Visual Analogue Scale; MMSE: Mini Mental State Examination; GDS: Geriatric Depression Scale; MNA-SF: Mini Nutritional Assessment - Short Form. ECOG PS: Eastern Cooperative Oncology Group - Performance Status.
  2. *In case of different denominator, the value is mentioned in the table.