From: Fall predictors in older cancer patients: a multicenter prospective study
Variable |  | Total population (n = 809)* | Non-fallers (no falls) (n = 667)* | Fallers (≥1 fall) (n = 142)* | Single fallers (1 fall) (n = 69)* | Recurrent fallers (≥2 falls) (n = 73)* | P-value non-fallers vs fallers | P-value non-fallers vs single fallers | P-value non-fallers vs recurrent fallers |
---|---|---|---|---|---|---|---|---|---|
Age | 70-74 | 322 (39.8%) | 278 (41.7%) | 44 (31.0%) | 23 (33.3%) | 21 (28.8%) | 0.0511 | 0.0955 | 0.1703 |
75-79 | 256 (31.6%) | 207 (31.0%) | 49 (34.5%) | 20 (29.0%) | 29 (39.7%) | ||||
≥80 | 231 (28.6%) | 182 (27.3%) | 49 (34.5%) | 26 (37.7%) | 23 (31.5%) | ||||
Gender | Female | 528 (65.3%) | 435 (65.2%) | 93 (65.5%) | 45 (65.2%) | 48 (65.8%) | 0.95 | 1.0 | 0.93 |
Male | 281 (34.7%) | 232 (34.8%) | 49 (34.5%) | 24 (34.8%) | 25 (34.3%) | ||||
G8 | No geriatric risk profile (>14) | 232 (28.7%) | 218 (32.7%) | 14 (9.9%) | 6 (8.7%) | 8 (11.0%) | <0.0001 | <0.0001 | 0.0001 |
Geriatric risk profile (≤14) | 577 (71.3%) | 449 (67.3%) | 128 (90.1%) | 63 (91.3%) | 65 (89.0%) | ||||
fTRST | No geriatric risk profile (0) | 153 (18.9%) | 147 (22.0%) | 6 (4.2%) | 2 (2.9%) | 4 (5.5%) | <0.0001 | 0.0002 | 0.0009 |
Geriatric risk profile (≥1) | 656 (81.1%) | 520 (78.0%) | 136 (95.8%) | 67 (97.1%) | 69 (94.5%) | ||||
ADL | Independent (6) | 413 (51.1%) | 375 (56.2%) | 38 (26.8%) | 16 (23.2%) | 22 (30.1%) | <0.0001 | <0.0001 | <0.0001 |
Dependent (≥7) | 396 (48.9%) | 292 (43.8%) | 104 (73.2%) | 53 (76.8%) | 51 (69.9%) | ||||
IADL | Independent (5(male)/8(female) | 367 (45.4%) | 325 (48.7%) | 42 (29.6%) | 18 (26.1%) | 24 (32.9%) | <0.0001 | 0.0003 | 0.01 |
Dependent (≤4(male)/≤7(female)) | 442 (54.6%) | 342 (51.3%) | 100 (70.4%) | 51 (73.9%) | 49 (67.1%) | ||||
Living situation | Not living alone | 571 (70.6%) | 486 (72.9%) | 85 (59.9%) | 42 (60.9%) | 43 (58.9%) | 0.002 | 0.0352 | 0.01 |
Living alone | 238 (29.4%) | 181 (27.1%) | 57 (40.1%) | 27 (39.1%) | 30 (41.1%) | ||||
Fall history in the past 12Â months | No falls | 566 (70.0%) | 510 (76.5%) | 56 (39.4%) | 32 (46.4%) | 24 (32.9%) | <0.0001 | <0.0001 | <0.0001 |
Falls (≥1) | 243 (30.0%) | 157 (23.5%) | 86 (60.6%) | 37 (53.6%) | 49 (67.1%) | ||||
CCI | No comorbidities (0) | 388 (48.0%) | 326 (48.9%) | 62 (43.7%) | 27 (39.1%) | 35 (47.9%) | 0.26 | 0.1230 | 0.88 |
Comorbidities (≥1) | 421 (52.0%) | 341 (51.1%) | 80 (56.3%) | 42 (60.9%) | 38 (52.1%) | ||||
MOB-T for fatigue | No fatigue | 339 (41.9%) | 313 (46.9%) | 26 (18.3%) | 12 (17.4%) | 14 (19.2%) | <0.0001 | <0.0001 | <0.0001 |
Fatigue | 470 (58.1%) | 354 (53.1%) | 116 (81.7%) | 57 (82.6%) | 59 (80.8%) | ||||
Poly-pharmacy | Absence (0–4 drugs) | 386/785 (49.2%) | 338/649 (52.1%) | 48/136 (35.3%) | 22/66 (33.3%) | 26/70 (37.1%) | 0.0004 | 0.0037 | 0.02 |
Presence (≥5 drugs) | 399/785 (50.8%) | 311/649 (47.9%) | 88/136 (64.7%) | 44/66 (66.7%) | 44/70 (62.9%) | ||||
VAS for pain | No pain (0) | 408 (50.4%) | 359 (53.8%) | 49 (34.5%) | 23 (33.3%) | 26 (35.6%) | <0.0001 | 0.0012 | 0.003 |
Mild pain/pain to treat (1–10) | 401 (49.6%) | 308 (46.2%) | 93 (65.5%) | 46 (66.7%) | 47 (64.4%) | ||||
MMSE | Normal cognition (≥24) | 738 (91.2%) | 615 (92.2%) | 123 (86.6%) | 59 (85.5%) | 64 (87.7%) | 0.03 | 0.0566 | 0.18 |
Mild/severe cognitive decline (≤23) | 71 (8.8%) | 52 (7.8%) | 19 (13.4%) | 10 (14.5%) | 9 (12.3%) | ||||
GDS | Not at risk for depression (0–4) | 663/806 (82.3%) | 559/665 (84.1%) | 104/141 (73.8%) | 52/68 (76.5%) | 52 (71.2%) | 0.004 | 0.1095 | 0.006 |
At risk for depression (≥5) | 143/806 (17.7%) | 106/665 (15.9%) | 37/141 (26.2%) | 16/68 (23.5%) | 21 (28.8%) | ||||
MNA-SF | Normal nutritional status (≥12) | 412 (50.9%) | 367 (55.0%) | 45 (31.7%) | 21 (30.4%) | 24 (32.9%) | <0.0001 | <0.0001 | 0.0003 |
Risk of malnutrition/malnourished (≤11) | 397 (49.1%) | 300 (45.0%) | 97 (68.3%) | 48 (69.6%) | 49 (67.1%) | ||||
ECOG PS | Score 0-1 | 619/808 (76.6%) | 529/666 (79.4%) | 90 (63.4%) | 42 (60.9%) | 48 (65.8%) | <0.0001 | 0.0004 | 0.0073 |
 | Score 2-4 | 189/808 (23.4%) | 137/666 (20.6%) | 52 (36.6%) | 27 (39.1%) | 25 (34.3%) |  |  |  |