Table 4 Risk of hip fracture during use of FRIDs in combined multimorbidity level groups adjusted for age and gender

Cardiovascular drugs

Odds ratio (95% CI)

Odds ratio (95% CI)

  Vasodilators used in cardiac diseases

0.96 (0.60-1.52)

0.94 (0.78-1.14)

  Antihypertensive agents

^**

1.51 (0.55-4.12)

  Diuretics

0.98 (0.73-1.33)

1.02 (0.86-1.20)

  Beta-blocking agents

0.89 (0.65-1.22)

0.98 (0.84-1.16)

  Calcium channel blockers

0.90 (0.60-1.34)

0.84 (0.68-1.03)

  Renin-angiotensin system inhibitors

0.75 (0.51-1.11)

1.02 (0.86-1.21)

Psychotropic drugs

  Opioids

1.45 (0.99-2.11)

1.71* (1.44-2.03)

  Dopaminergic agents

1.51 (0.47-4.81)

1.91* (1.31-2.79)

  Antipsychotics excluding lithium

1.86* (1.07-3.22)

1.22 (0.87-1.72)

  Anxiolytics

1.37 (0.95-1.98)

1.35* (1.12-1.63)

  Hypnotics and sedatives

1.37 (0.99-1.90)

1.36* (1.15-1.61)

  Antidepressants

1.66* (1.16-2.37)

1.75* (1.47-2.09)