Skip to main content

Advertisement

Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

Table 2 Risk of hip fracture in patients using FRIDs

From: Is use of fall risk-increasing drugs in an elderly population associated with an increased risk of hip fracture, after adjustment for multimorbidity level: a cohort study

Drugs/group of drugs Model A Model B Model C Model D
Cardiovascular drugs Odds ratio (95% CI) Odds ratio (95% CI) Odds ratio (95% CI) Odds ratio (95% CI)
  Vasodilators used in cardiac diseases 1.14 (0.96-1.35) 0.99 (0.83-1.18) 1.02 (0.85-1.21) 0.89 (0.74-1.06)
  Antihypertensive agents 0.99 (0.37-2.67) 1.12 (0.41-3.02) 1.29 (0.47-3.49) 1.26 (0.46-3.42)
  Diuretics 1.35* (1.17-1.56) 1.10 (0.95-1.27) 1.07 (0.92-1.23) 0.97 (0.84-1.12)
  Beta-blocking agents 0.96 (0.83-1.11) 1.01 (0.88-1.16) 1.01 (0.88-1.17) 0.92 (0.80-1.07)
  Calcium channel blockers 0.82* (0.68-0.98) 0.87 (0.73-1.05) 0.88 (0.73-1.05) 0.83 (0.69-1.00)
  Renin-angiotensin system inhibitors 0.89 (0.77-1.04) 0.99 (0.85-1.16) 1.02 (0.87-1.19) 0.93 (0.79-1.09)
Psychotropic drugs     
  Opioids 2.03* (1.75-2.36) 1.83* (1.57-2.13) 1.76* (1.51-2.05) 1.56* (1.34–1.82)
  Dopaminergic agents 1.88* (1.31-2.67) 1.96* (1.37-2.81) 1.99* (1.39-2.84) 1.78* (1.24-2.55)
  Antipsychotics excluding lithium 1.80* (1.35-2.39) 1.42* (1.06-1.89) 1.37* (1.03-1.84) 1.31 (0.98-1.75)
  Anxiolytics 1.75* (1.49-2.06) 1.48* (1.25-1.74) 1.41* (1.19-1.66) 1.31* (1.11-1.54)
  Hypnotics and sedatives 1.75* (1.51-2.02) 1.48* (1.28-1.71) 1.42* (1.22-1.64) 1.31* (1.13-1.52)
  Antidepressants 2.08* (1.78-2.43) 1.88* (1.61-2.20) 1.79* (1.53-2.10) 1.66* (1.42-1.95)
  1. *p-value <0.05.
  2. Model A was unadjusted; Model B was adjusted for age; Model C was adjusted for age and gender; and Model D was adjusted for age, gender and multimorbidity level.