Table 2 Risk of hip fracture in patients using FRIDs

Cardiovascular drugs

Odds ratio (95% CI)

Odds ratio (95% CI)

Odds ratio (95% CI)

Odds ratio (95% CI)

  Vasodilators used in cardiac diseases

1.14 (0.96-1.35)

0.99 (0.83-1.18)

1.02 (0.85-1.21)

0.89 (0.74-1.06)

  Antihypertensive agents

0.99 (0.37-2.67)

1.12 (0.41-3.02)

1.29 (0.47-3.49)

1.26 (0.46-3.42)

  Diuretics

1.35* (1.17-1.56)

1.10 (0.95-1.27)

1.07 (0.92-1.23)

0.97 (0.84-1.12)

  Beta-blocking agents

0.96 (0.83-1.11)

1.01 (0.88-1.16)

1.01 (0.88-1.17)

0.92 (0.80-1.07)

  Calcium channel blockers

0.82* (0.68-0.98)

0.87 (0.73-1.05)

0.88 (0.73-1.05)

0.83 (0.69-1.00)

  Renin-angiotensin system inhibitors

0.89 (0.77-1.04)

0.99 (0.85-1.16)

1.02 (0.87-1.19)

0.93 (0.79-1.09)

Psychotropic drugs

  Opioids

2.03* (1.75-2.36)

1.83* (1.57-2.13)

1.76* (1.51-2.05)

1.56* (1.34–1.82)

  Dopaminergic agents

1.88* (1.31-2.67)

1.96* (1.37-2.81)

1.99* (1.39-2.84)

1.78* (1.24-2.55)

  Antipsychotics excluding lithium

1.80* (1.35-2.39)

1.42* (1.06-1.89)

1.37* (1.03-1.84)

1.31 (0.98-1.75)

  Anxiolytics

1.75* (1.49-2.06)

1.48* (1.25-1.74)

1.41* (1.19-1.66)

1.31* (1.11-1.54)

  Hypnotics and sedatives

1.75* (1.51-2.02)

1.48* (1.28-1.71)

1.42* (1.22-1.64)

1.31* (1.13-1.52)

  Antidepressants

2.08* (1.78-2.43)

1.88* (1.61-2.20)

1.79* (1.53-2.10)

1.66* (1.42-1.95)