Association of biomarkers of inflammation and cell adhesion with lung function in the elderly: a population-based study

Table 3 Association between inflammatory markers and lung function

	FEV₁% predicted	p-value	FVC % predicted	p-value
Leukocyte count	−1.64 (−3.03, -0.24)	0.02	−1.77 (−2.96, -0.58)	0.005
CRP	−1.71 (−3.09, -0.32)	0.02	-
EGF	1.23 (−0.002, 2.46)	0.05	1.05 (−0.06, 2.15)	0.06
VCAM-1*	-		−1.28 (−2.45, -0.11)	0.03
ICAM-1**	−0.97 (−2.30, 0.36)	0.13	-
Women	3.42 (0.90-5.94)	0.008	11.8 (9.54, 14.1)	<0.0001
BMI	0.05 (−0.26,0.36)	0.70	−0.29 (−0.56, -0.02)	0.04
Current smoking	−6.61 (−11.2,-1.99)	0.005	−0.21 (−4.27, 3.86)	0.96
Pack years	−0.30, (−0.41, -0.18)	<0.0001	−0.15 (−0.24, -0.04)	0.005

All estimates are adjusted for each of the included inflammatory markers, pack years, current smoking status, gender, and BMI.
Values are β-coefficient (95% CI), in % per 1 SD change in biomarker.
* Only included in model with FVC as dependent variable.
** Only included in model with FEV₁ as dependent variable.

ISSN: 1471-2318