Insights into the clinical management of the syndrome of supine hypertension – orthostatic hypotension (SH-OH): The Irish Longitudinal Study on Ageing (TILDA)

Table 5 Contribution of MOH-3 and OI towards history of blackout or faints in the presence of potential confounders

Full sample	B	Std. error	P	Odds ratio	95% wald confidence interval for odds ratio
Full sample	B	Std. error	P	Odds ratio	Lower	Upper
OI	0.24	0.08	0.003	1.27	1.09	1.48
Female sex	0.30	0.08	<0.001	1.35	1.16	1.57
Polypharmacy	0.32	0.10	0.002	1.37	1.12	1.68
N03A (antiepileptics)	0.87	0.21	<0.001	2.39	1.57	3.63
N06A (antidepressants)	0.48	0.14	0.001	1.62	1.22	2.15
Transient Ischemic Attack	0.66	0.26	0.013	1.93	1.15	3.25
Abnormal heart rhythm	0.67	0.13	<0.001	1.95	1.49	2.53
Age	−0.01	0.00	0.013	0.99	0.98	1.00
Subsample ≥70 years old	B	Std. error	P	Odds ratio	95% wald confidence interval for odds ratio
Subsample ≥70 years old	B	Std. error	P	Odds ratio	Lower	Upper
Female sex	0.45	0.19	0.014	1.58	1.10	2.26
Polypharmacy	0.42	0.19	0.028	1.52	1.05	2.20
N03A (antiepileptics)	1.57	0.45	<0.001	4.82	2.00	11.61
Abnormal heart rhythm	0.84	0.24	<0.001	2.31	1.45	3.67

Dependent variable: Ever had a blackout or fainted. Binary logistic response, forward conditional procedure. Predictors entered: female sex, polypharmacy, C01A (cardiac glycosides), C01B (antiarrhythmics), C07A (beta blockers), C03 (diuretics), C09A (ACE-i), C09C (ARA), C08C (peripheral CCB), C08D (cardiac CCB), C02C (alpha blockers), C01D (cardiac vasodilators), C04A (peripheral vasodilators), N03A (antiepileptics), N05A (antipsychotics), N05B (anxiolytics), N05C (hypnotics, sedatives), N06A (antidepressants), hypertension, angina, heart attack, heart failure, diabetes, stroke¸ TIA, abnormal heart rhythm, Parkinson’s disease, three or more chronic diseases, any IADL disability, age, MOH-3, MMSE, OI.

ISSN: 1471-2318