Insights into the clinical management of the syndrome of supine hypertension – orthostatic hypotension (SH-OH): The Irish Longitudinal Study on Ageing (TILDA)

Table 3 Generalised linear model to predict MOH-3 membership

Full sample	B	Std. error	P	Odds ratio	95% wald confidence interval for odds ratio
Full sample	B	Std. error	P	Odds ratio	Lower	Upper
Female sex	0.55	0.08	<0.001	1.73	1.46	2.04
C07A (beta blockers)	0.47	0.12	<0.001	1.60	1.26	2.04
C08C (peripheral CCB)	−0.38	0.16	<0.001	0.68	0.49	0.94
N06A (antidepressants)	0.69	0.14	<0.001	1.99	1.50	2.64
Heart attack	−0.47	0.23	0.042	0.62	0.40	0.98
age	0.03	0.00	<0.001	1.03	1.03	1.04
Subsample ≥70 years old	B	Std. error	P	Odds ratio	95% wald confidence interval for odds ratio
Subsample ≥70 years old	B	Std. error	P	Odds ratio	Lower	Upper
Female sex	0.34	0.17	0.040	1.41	1.02	1.96
C07A (beta blockers)	0.44	0.19	0.021	1.55	1.07	2.25
C08C (peripheral CCB)	−0.60	0.27	0.025	0.55	0.33	0.93
N06A (antidepressants)	0.70	0.30	0.018	2.01	1.13	3.60
Diabetes	−0.62	0.33	0.064	0.54	0.28	1.04
Age	0.05	0.02	0.009	1.05	1.01	1.09

Dependent variable: MOH type 3 (large drop, under-recovery). Binary logistic response, forward conditional procedure. Predictors entered: female sex, polypharmacy, C01A (cardiac glycosides), C01B (antiarrhythmics), C07A (beta blockers), C03 (diuretics), C09A (ACE-i), C09C (ARA), C08C (peripheral CCB), C08D (cardiac CCB), C02C (alpha blockers), C01D (cardiac vasodilators), C04A (peripheral vasodilators), N03A (antiepileptics), N05A (antipsychotics), N05B (anxiolytics), N05C (hypnotics, sedatives), N06A (antidepressants), hypertension, angina, heart attack, heart failure, diabetes, stroke¸ TIA, abnormal heart rhythm, Parkinson’s disease, three or more chronic diseases, any IADL disability, age.

ISSN: 1471-2318