Table 1 Baseline and follow-up characteristics of the male and female study participants by birth year at baseline

46

51

55

50.8 ± 0.3

60.2 ± 0.4

60.6 ± 0.4

70.3 ± 0.4

72.1 ± 3.7

81.8 ± 3.7

177.8 ± 6.1

177.6 ± 6.1

173.5 ± 5.6

173.6 ± 5.8

173.0 ± 5.8

172.8 ± 5.9

79.7 ± 11.8

81.1 ± 13.4

78.8 ± 10.8

79.7 ± 10.7

77.3 ± 10.6

75.1 ± 11.7**

20/24

28/15

29/35

48/22*

38/18

49/11

74 ± 56

81 ± 49

72 ± 54

78 ± 68

73 ± 57

76 ± 61

10.9

21.7

17.6

37.3**

29.1

54.5***

2.2

2.2

7.8

5.9

5.5

18.2*

50.0

65.2

47.1

51.0

50.9

67.3

671 ± 69

619 ± 95***

645 ± 82

595 ± 84***

609 ± 96

547 ± 101***

1.28 ± 0.21

0.90 ± 0.20***

1.19 ± 0.27

0.86 ± 0.22***

0.94 ± 0.26

0.68 ± 0.23***

149 ± 19

143 ± 27

134 ± 22

122 ± 29**

126 ± 26

95 ± 27***

2.03 ± 0.33

2.05 ± 0.30

1.78 ± 0.30

1.69 ± 0.33

1.71 ± 0.29

1.49 ± 0.38***

70

70

66

51.0 ± 0.5

60.3 ± 0.4

60.7 ± 0.4

70.3 ± 0.4

72.1 ± 3.6

81.9 ± 3.6

163.8 ± 5.8

163.8 ± 5.6

161.8 ± 6.7

162.2 ± 6.6

161.3 ± 5.0

161.1 ± 5.0

66.8 ± 10.3

69.8 ± 11.1***

70.1 ± 13.3

71.8 ± 15.5*

70.6 ± 13.6

67.6 ± 12.4***

13.6 ± 1.4

-

14.2 ± 1.5

-

14.1 ± 1.4

-

42.9

100

100

100

100

100

46.3 ± 3.6

52.6 ± 1.9

50.3 ± 3.5

-

48.5 ± 4.7

-

4.7 ± 3.4

10.6 ± 4.0

10.4 ± 3.5

20.0 ± 3.5

23.6 ± 6.1

33.4 ± 6.1

20.3

47.8***

11.4

24.3*

7.7

10.9

13/36

23/27*

14/16

19/16

11/5

11/5

43 ± 63

49 ± 48

44 ± 28

38 ± 18

57 ± 40

52 ± 44

17.1

34.3***

30.0

45.7**

43.1

66.7***

8.6

7.1

4.3

4.3

15.2

25.8

85.7

78.6

82.9

68.6*

84.8

83.3

527 ± 55

492 ± 77***

477 ± 61

409 ± 66***

418 ± 81

355 ± 79***

0.88 ± 0.23

0.67 ± 0.17***

0.79 ± 0.20

0.59 ± 0.15***

0.62 ± 0.12

0.47 ± 0.13***

140 ± 20

136 ± 26

127 ± 18

107 ± 22***

113 ± 26

88 ± 28***

1.65 ± 0.32

1.64 ± 0.37

1.56 ± 0.27

1.55 ± 0.37

1.43 ± 0.24

1.18 ± 0.38***