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Table 3 Relationships between both the eGFR at age 88 years and the decrease in the eGFR 3 years before (between age 85 and 88) and total and cardiovascular (CV) mortality

From: Prediction of mortality and functional decline by changes in eGFR in the very elderly: the Leiden 85-plus study

 

eGFR slope per year between 85 and 88 years in ml/min/1.73 m2/year

>-1

-1 to -2.99

-3 to -4.99

<-5

eGFR at age 88 > 60 (n=169)

 

n=128

n=26

n=12

n=3

Overall mortality

1 (ref)

1.37 (0.82-2.31)

2.17 (1.08-4.40)

2.63 (0.79-8.76)

CV mortality

1 (ref)

1.10 (0.39-3.05)

2.99 (1.02-9.07)

8.35 (2.15-32.46)

eGFR at age 88

4559 (n=147)

 

n=71

n=46

n=21

n=9

Overall mortality

1 (ref)

0.77 (0.47-1.26)

1.27 (0.69-2.35)

3.16 (1.44-6.95)

CV mortality

1 (ref)

0.89 (0.38-2.07)

0.67 (0.18-2.78)

4.23 (1.22-14.65)

eGFR at age 88 < 45 (n=62)

 

n=20

n=21

n=14

n=7

Overall mortality

1 (ref)

0.63 (0.31-1.26)

0.54 (0.18-1.61)

2.03 (0.59-7.02)

CV mortality

1 (ref)

0.99 (0.39-2.55)

0.34 (0.04-2.76)

4.72 (1.21-18.47)

  1. The results are presented as the HR (95% CI) and were adjusted for gender and the mean of the eGFR at ages 85 and 88. The results are shown with one reference group for each eGFR subgroup.
  2. * No events.