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Table 2 Clinical outcomes according to laxative use and drug class

From: Laxative use and incident falls, fractures and change in bone mineral density in postmenopausal women: results from the Women’s Health Initiative

Clinical outcome

No Laxative use (N=151497)

Laxative use (N=8907)

Oral stimulant containing laxative (N=1603)

Fiber containing laxative (N=5372)

Osmotic containing laxative (N=281)

Stool softener containing laxative (N=2525)

Lubricant containing laxative (N=33)

Falls (> 2)

50175 (33.9%)

3484 (40.0%)

588 (37.7%)

2040 (38.8%)

106 (39.3%)

1067 (43.3%)

15 (46.9%)

p-yrs

959,729

53,592

     

Follow-up yrs (SD) / person

6.4 (2.7)

6.1 (2.7)

Hip fracture

1706 (1.1%)

142 (1.6%)

33 (2.1%)

73 (1.4%)

4 (1.4%)

52 (2.1%)

0 (0.0%)

p-yrs

1,171,740

67,909

     

Follow-up yrs (SD) / person

7.8 (1.6)

7.6 (1.7)

Total fracture

21642 (14.3%)

1476 (16.6%)

255 (15.9%)

852 (15.9%)

48 (17.1%)

449 (17.8%)

6 (18.2%)

p-yrs

1,053,650

61,029

     

Follow-up yrs (SD) / person

7.2 (2.2)

7.1 (2.2)