Table 3 BIM neuropsychological assessment
Domain | Test | Description |
|---|---|---|
Attention | Computerized test of the efficiency of 3 attention networks, including tests of altering, orienting and executive control (flanker test) | |
Auditory Consonant Trigram Test [54] | Auditory presentation of 3 consonant trigrams (i.e., three single consonant letters) followed by a number. The subject is instructed to subtract from that number for several seconds until cued, and then asked to recall the letters | |
Processing Speed | Symbol-Digit Modalities [55] | Simple substitution task pairing specific numbers with given geometric figures. Both written (90 seconds) and oral (90 seconds) forms administered |
Verbal Memory | 1. Memory Test (List learning of 12 words rehearsed for six trials) | |
2. Cued Recall | ||
3. Multiple Choice recognition | ||
4. Oral delayed recall of 12 words (30 minutes following multiple choice) | ||
Visual Memory | Medical College of Georgia Complex Figures Test (MCG) [58] | A test of visual memory in which the subject is asked to copy the figure and then draws it from memory at an immediate test and at a 30 minute delay |
Executive Function | Delis-Kaplan Executive Function System (D-KEFS) [59] | 1. Card Sorting Test- one card set is randomly assigned to each session (i.e., one card set per phase) in which the free-sorting and recognition conditions are tested |
2. Color-word Interference Test- four conditions are presented to participants (i.e., colour naming, word reading, inhibition, and inhibition/switching) and participants must follow the presented rule to orally complete the task as accurately as possible | ||
3. Verbal Fluency Test- participants must say as many words as possible in 60 seconds for each condition (i.e., letter fluency, category fluency, and category switching) | ||
Premorbid Intellectual Ability | North American Adult Reading Test [60] | 61 different rare words are presented with scoring based on American and Canadian punctuation rules |
Mood | 65 adjectives are presented that are rated by subjects using a 5-point scale. From the responses 6 factors are derived (tension-anxiety, vigour-activity, depression-dejection, fatigue-inertia, anger-hostility, and confusion-bewilderment | |
Sleep | Pittsburg Sleep Quality Index [47] | Self-report questionnaire of the last month sleep habits/sleep quality |
Epworth Sleepiness Scale [48] | Self-report of general daytime sleepiness | |
Social Support | Modified version of the Lubben Social Network Scale [50] | Self-report questionnaire of perceived social support from family, friends, and other study participants |
Cognitive Activity | Lifetime Cognitive Questionnaire (Test 1A only) [62] | 20 questions that assess cognitive activities participants were engaged in during childhood (age 6), teens (age 12), young adults (age 18), and adulthood (age 40) |
| Â | Current Cognitive Questionnaire (all test sessions) [62] | 23 questions that assess the degree to which participants are cognitively active in their lives at the present time |