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Table 1 Demographics and clinical characteristics of subjects (n = 33) and associations with C22:0 and C24:0 concentrations

From: Ceramides predict verbal memory performance in coronary artery disease patients undertaking exercise: a prospective cohort pilot study

 

CAD (n = 33) Mean ± SD or % (n)

Statistic (F or r)

C22:0 P-value (p ≤ 0.05)*

Statistic (F or r)

C24:0 P-value (p ≤  0.05)*

Sociodemographics

Age (yrs)

62 ± 9

r = −0.24

0.18

r = −0.38

0.03*

Sex (% male)

84.8 (28)

F = 0.16

0.69

F = 0.12

0.74

Ethnicity (% Caucasian)

90.9 (30)

F = 0.81

0.38

F = 0.28

0.60

Marital status (% married)

75.8 (25)

F = 2.56

0.12

F = 2.00

0.17

Employed (% employed)

48.5 (16)

F = 0.03

0.86

F = 0.07

0.79

Years of education (yrs)

17 ± 3

r = −0.01

0.97

0.09

0.62

Body composition

Body mass index (kg/m2)

28.2 ± 3.6

r = 0.27

0.13

r = 0.27

0.13

Body fat (%)

28.3 ± 7.4

r = 0.24

0.19

r = 0.19

0.29

Body mass (pounds)

185.1 ± 27.3

r = 0.22

0.22

r = 0.27

0.13

Waist circumference (cm)

99.6 ± 9.7

r = 0.08

0.68

r = 0.08

0.67

CAD severity

Cumulative stenosis (%)

132.9 ± 45.9

r = 0.05

0.78

r = 0.06

0.73

Number of vessels stenosed

2 ± 1

r = 0.02

0.92

r = 0.11

0.54

Time since acute coronary event (wks)

28.7 ± 76.7

r = 0.09

0.61

r = 0.11

0.53

Cardiac history % (n)

Myocardial infarction

54.5 (18)

F = 1.38

0.25

F = 3.40

0.08

Coronary artery bypass graft surgery

39.4 (13)

F = 0.97

0.33

F = 1.79

0.19

Stent

57.6 (19)

F = 1.20

0.28

F = 3.94

0.06

Angina

27.3 (9)

F = 0.55

0.46

F = 0.89

0.35

Hypertension

57.6 (19)

F = 0.65

0.43

F = 0.30

0.59

Comorbidities % (n)

Diabetes

15.2 (5)

F = 0.85

0.37

F = 1.09

0.30

Depression

36.4 (12)

F = 1.48

0.23

F = 1.19

0.28

Hypercholesterolemia

100 (33)

-

-

-

-

Cardiopulmonary fitness parameters

Maximum heart rate (bpm)

124.3 ± 19.6

r = 0.13

0.46

r = 0.18

0.33

Maximum systolic blood pressure (mm Hg)

181.6 ± 28.3

r = 0.15

0.40

r = 0.06

0.73

Maximum diastolic blood pressure (mm Hg)

82.4 ± 11.6

r = −0.004

0.98

r = 0.01

0.94

VO2 peak (ml/kg/min)

20.7 ± 5.3

r = −0.13

0.49

r = −0.10

0.60

Medications % (n)

B-blocker

81.8 (27)

F = 0.17

0.68

F = 0.01

0.93

Diuretic

21.2 (7)

F = 0.90

0.35

F = 0.15

0.70

Anti-hypertensive

57.6 (19)

F = 0.67

0.42

F = 0.13

0.72

Ca2+ channel blocker

12.1 (4)

F = 0.11

0.74

F = 0.35

0.56

Antidiabetic

9.1 (3)

F = 0.65

0.43

F = 0.25

0.62

Statin

100 (33)

-

-

-

-

Anxiolytic

6.1 (2)

F = 0.84

0.37

F = 0.69

0.41

Antidepressant

6.1 (2)

F = 0.30

0.59

F = 0.41

0.53

  1. *two-tailed significance in one-way ANOVA or Pearson correlations.