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Table 2 Selected concomitant medication use among elderly subjects during the CONFIRMS trial

From: The efficacy and safety of febuxostat for urate lowering in gout patients ≥65 years of age

 

Febuxostat 40 mg

N = 115

Febuxostat 80 mg

N = 128

Allopurinol 200/300 mg

N = 131

  

n (%)

 

Subjects with one or more concomitant medication

   

Agents acting on the renin-angiotensin systema

65 (57)

78 (61)

83 (63)

Analgesics

23 (20)

33 (26)

27 (21)

Antiinflammatory and antirheumatic products

26 (23)

32 (25)

26 (20)

Antithrombotic agents

58 (50)

65 (51)

65 (50)

Beta blockers

45 (39)

43 (34)

55 (42)

Calcium channel blockers

19 (17)

21 (16)

30 (23)

Corticosteroids for systemic use

12 (10)

21 (16)

15 (11)

Drugs for acid-related gastrointestinal disorders

23 (20)

32 (25)

34 (26)

Drugs used in diabetes

20 (17)

25 (20)

29 (22)

Diuretics

26 (23)

32 (25)

33 (25)

Lipid modifying agents

64 (56)

69 (54)

75 (57)

Other antihypertensivesb

13 (11)

4 (3)

10 (8)

  1. aAgents acting on the renin-angiotensin system include a direct renin inhibitor, angiotensin II receptor blockers, and angiotensin-converting enzyme inhibitors.
  2. bIncludes vasodilators, alpha-blockers, and α-adrenergic receptor agonists.